ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2021
Apathy: Neurobiology, Assessment and Treatment.
Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Repetitive transcranial magnetic stimulation for apathy in patients with neurodegenerative conditions, cognitive impairment, stroke, and traumatic brain injury: a systematic review.Frontiers in psychiatry · 2023Pooled it
- Vascular disease and apathy symptoms in the very old: A cross-sectional and longitudinal meta-analysis of individual participant data.International journal of geriatric psychiatry · 2022Pooled it
- Latent profiles of apathy in the general population and their associations with psychopathology and functioning.Scientific reports · 2026Article
- Bilateral DLPFC transcranial direct current stimulation for mood and motor symptoms in Parkinson's disease: a preliminary study.Acta neuropsychiatrica · 2026Article
- Apathy in the elderly: an atypical manifestation of spotted fever rickettsioses.BMC geriatrics · 2026Article
- Depression and apathy: examining an overlooked dimension.Annals of general psychiatry · 2026Article
- Apathy and Depression Impact on Cognitive Decline: Neuropsychological Specificities across Neurodegenerative Diseases.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026Article
- From dysphoria to anhedonia: age-related shift in the link between cognitive and affective symptoms.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Distinct Computational Mechanisms of Uncertainty Processing Explain Opposing Exploratory Behaviors in Anxiety and Apathy.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Exploring apathy components and their relationship in cognitive decline: insights from a network cross-sectional study.BMC psychology · 2025Article
- Behavioral and Psychological Symptoms (BPSD) in Alzheimer's Disease (AD): Development and Treatment.Current topics in behavioral neurosciences · 2025Review
- Investigating the Prevalence and Predictors of Apathy among the Canadian Long-Term Care Residents: A Secondary Data Analysis.The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres · 2024Article
- Article
- Future Therapeutic Strategies for Alzheimer's Disease: Focus on Behavioral and Psychological Symptoms.International journal of molecular sciences · 2024Review
- Associations between neuropsychiatric symptoms and incident Alzheimer's dementia in men versus women.Journal of neurology · 2023Article
- Parkinson's Disease: Diagnostic Challenges Amidst Transdiagnostic and Overlapping Mental Health Symptoms.Cureus · 2023Article
- Particulate Air Pollution and Risk of Neuropsychiatric Outcomes. What We Breathe, Swallow, and Put on Our Skin Matters.International journal of environmental research and public health · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Apathy is a highly prevalent, disabling and treatment resistant syndrome. It is defined as a quantitative reduction of goal-directed activity in comparison to the patient's previous level of in multiple dimensions including behavior/cognition, emotion and social interaction. It has been described in major depressive disorder, Alzheimer's disease, frontotemporal dementia, Parkinson's Disease, cerebrovascular disease, and vascular dementia, among others. This review will address the neuropsychology and associated neurobiological underpinnings of apathy in the above conditions, identify specific methods to assess apathy clinically, and review the literature on managing apathy across these various disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.