ArticleScience (New York, N.Y.)2021
C(sp
Article in Science (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 205 citations in OpenAlex.
- The Preparation and Systematic Evaluation of Ligated Ni(II) Pre-Catalysts (NiPC) in Common Single Electron Cross-Coupling Reactions.ACS medicinal chemistry letters · 2026Article
- Copper(II/III) Redox Couple Enables C─H Methylation via a Radical Mechanism Analogous to SAM Enzymes.Angewandte Chemie (International ed. in English) · 2026Article
- Ligand-modulated metal-radical polarity match enables general 1,2-dicarbofunctionalization of ethylene.Nature chemistry · 2026Article
- Enantioconvergent Chan-Evans-Lam C(spJournal of the American Chemical Society · 2026Article
- Overcoming the Barrier to Intermolecular Alkoxy Radical Reactivity: Proton-Coupled Electron Transfer-Mediated Alkene Hydroetherification.Journal of the American Chemical Society · 2026Article
- Nickel-Catalyzed Cross-Dehydrogenative Allylation of Aldehydes.Journal of the American Chemical Society · 2026Article
- Cobalt-Catalyzed Four-Component Carbonylative Synthesis of γ-Thioesters and γ-Thioamides from Thioethers and Ethylene.Organic letters · 2025Article
- Three-Component 1,2-Methylamidation of Alkynes via Coordinating Activation Strategy.ChemistryOpen · 2025Article
- Bioinspired transfer methylation enabled by a photoactive reagent.Nature communications · 2025Article
- Diversification of Pharmaceuticals via Late-Stage Hydrazination.ACS catalysis · 2025Article
- Evolving Landscape: Accounts of Academic-Industrial Collaborations in Chemistry Technology.ACS medicinal chemistry letters · 2025Review
- Rapid Methylation of Aryl Bromides Using Air-Stable DABCO-Bis(Trimethylaluminum) via Nickel Metallaphotoredox Catalysis.Angewandte Chemie (International ed. in English) · 2025Article
- Radical Sorting Catalysis via Bimolecular Homolytic Substitution (SJournal of the American Chemical Society · 2025Review
- Late-Stage Heteroarene Alkylation via Minisci Reaction with Gaseous Alkanes Enabled by Hydrogen Atom Transfer in Flow.ACS central science · 2025Article
- Photoinduced Copper-Catalyzed Enantioselective Allylic C(Journal of the American Chemical Society · 2025Article
- Enantioselective β-C(spJournal of the American Chemical Society · 2025Article
- Dehomologative C-C Borylation of Aldehydes and Alcohols via a Rh-Catalyzed Dehydroformylation-Borylation Relay.Journal of the American Chemical Society · 2025Article
- Quinoline Quest: Kynurenic Acid Strategies for Next-Generation Therapeutics via Rational Drug Design.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Direct stereoselective C(spNature chemistry · 2025Article
- Stereoselective alkylation of saturated heterocycles.Nature chemistry · 2025Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The "magic methyl" effect describes the change in potency, selectivity, and/or metabolic stability of a drug candidate associated with addition of a single methyl group. We report a synthetic method that enables direct methylation of C(sp
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.