Trial reportClinical journal of the American Society of Nephrology : CJASN2021
Targeting Sedentary Behavior in CKD: A Pilot and Feasibility Randomized Controlled Trial.
Trial report in Clinical journal of the American Society of Nephrology : CJASN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02970123 (Sit Less, Interact, Move More), which is not on this map. Cited by 14 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sit Less, Interact, Move More (SLIMM) Intervention for Sedentary Behavior in Chronic Kidney Disease (CKD)
Who cites it
14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Pooled it
- Interventions to reduce sedentary behaviour in community-dwelling older adults: a mixed-method review.The international journal of behavioral nutrition and physical activity · 2025Pooled it
- Prescribing Physical Activity and Exercise for People with CKD: A Practical Guide by the Global Renal Exercise Network.Clinical journal of the American Society of Nephrology : CJASN · 2025Guideline
- Objectively measured daily steps as an outcome in a clinical trial of chronic kidney disease: a systematic review.BMC nephrology · 2024Pooled it
- Daily Step Counts in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis of Observational Studies.Frontiers in medicine · 2022Pooled it
- Sedentary behavior as an emerging risk factor for chronic kidney disease: a narrative review.Clinical and experimental nephrology · 2026Review
- Physical activity in kidney disease: evidence and implementation.Nature reviews. Nephrology · 2025Review
- Understanding for whom, under which circumstances and how sedentary behaviour interventions for older adults work: a realist review.BMJ open · 2025Review
- Nonpharmacologic and Nonsurgical Weight Management Interventions for Patients With Advanced CKD: A Scoping Review of the Medical Literature.Kidney medicine · 2025Review
- Physical Activity Levels in Transplant Recipients.Annals of transplantation · 2024Article
- Emerging Preventive Strategies in Chronic Kidney Disease: Recent Evidence and Gaps in Knowledge.Current atherosclerosis reports · 2023Review
- An intervention to decrease sedentary behavior in older adults: A secondary analysis of a randomized controlled trial.Obesity science & practice · 2023Article
- High physical activity alleviates the adverse effect of higher sedentary time on the incidence of chronic kidney disease.Journal of cachexia, sarcopenia and muscle · 2023Article
- The "adult inactivity triad" in patients with chronic kidney disease: A review.Frontiers in medicine · 2023Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesWe tested the feasibility of reducing sedentary behavior common in CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We carried out a Sit Less, Interact, Move More intervention in a 24-week parallel-group, randomized controlled trial in patients with stages 2-5 CKD. In the intervention group (
resultsThe mean age was 69±13 years. Fourteen percent were on dialysis or received a kidney transplant. Eight percent of the control group and 17% of the intervention group were lost to follow-up. Sedentary and stepping durations did not change in the control group. Within the intervention group, the maximum decrease in sedentary duration (-43; 95% confidence interval, -69 to -17 min/d) and increase in stepping duration (16; 95% confidence interval, 7 to 24 min/d) and the number of steps per day (1265; 95% confidence interval, 518 to 2012) were seen at week 20. These attenuated at week 24. In mixed effects models, overall treatment effects between groups on sedentary (-17; 95% confidence interval, -43 to 8 min/d) and stepping (6; 95% confidence interval, -3 to 15 min/d) durations and the number of steps per day, a secondary end point (652; 95% confidence interval, -146 to 1449), were not significantly different. The intervention significantly reduced secondary end points of body mass index (-1.1; 95% confidence interval, -1.9 to -0.3 kg/m
conclusionsIt is feasible to reduce sedentary duration and increase stepping duration in patients with CKD, but these were not sustained. CLINICAL TRIAL REGISTRY NAME AND REGISTRATION NUMBER: National Health and Nutrition Examination Survey (NHANES), NCT02970123.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.