Evidence map›Paper›PMID 33888512›Full record

ArticleGenome research2021

Modeling transcriptional regulation of model species with deep learning.

Evan M Cofer, João Raimundo, Alicja Tadych, Yuji Yamazaki, Aaron K Wong, Chandra L Theesfeld, Michael S Levine, Olga G Troyanskaya

Abstract read
In one paragraph

Article in Genome research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
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  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Evan M CoferLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA.ORCID 0000-0003-3877-0433
João RaimundoLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA.ORCID 0000-0002-8976-1898
Alicja TadychLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA.ORCID 0000-0001-8645-0739
Yuji YamazakiLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA.
Aaron K WongFlatiron Institute, Simons Foundation, New York, New York 10010, USA.ORCID 0000-0002-7294-0646
Chandra L TheesfeldLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA.ORCID 0000-0002-8379-6600
Michael S LevineLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA.
Olga G TroyanskayaLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA.ORCID 0000-0002-5676-5737

Funding

Quantitavie and Computational Biology Graduate ProgramT32HG003284 · NHGRI · PRINCETON UNIVERSITY · PI Joshua Michael Akey, Stanislav Y. Shvartsman · 2004 to 2026
$9.9M
Visualization of gene activity in the Drosophila embryoR35GM118147 · NIGMS · PRINCETON UNIVERSITY · PI Michael Steven Levine · 2016 to 2026
$6.7M
lntegration and Visualization of Diverse Biological DataR01GM071966 · NIGMS · PRINCETON UNIVERSITY · PI TROYANSKAYA, OLGA G · 2005 to 2022
$6.4M
NHGRI NIH HHS T32 HG003284NIGMS NIH HHS R01 GM071966NIGMS NIH HHS R35 GM118147
6 · The paper itself

Abstract

To enable large-scale analyses of transcription regulation in model species, we developed DeepArk, a set of deep learning models of the

Indexed as

Deep LearningDrosophila melanogasterAnimalsCaenorhabditis elegansGene Expression RegulationMiceZebrafish

Identifiers

PMID33888512
PMCPMC8168591

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.