Evidence map›Paper›PMID 33888511›Full record

ArticleGenome research2021

Comprehensive characterization of tissue-specific chromatin accessibility in L2

Timothy J Durham, Riza M Daza, Louis Gevirtzman, Darren A Cusanovich, Olubusayo Bolonduro, William Stafford Noble, Jay Shendure, Robert H Waterston

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. A molecular timer couples organism-wide temporal identity to developmental checkpoints.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. A developmental timer coordinates organism-wide microRNA transcription.bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. A scheduler for rhythmic gene expression.Molecular systems biology · 2025
    Article
  9. Article
  10. A scheduler for rhythmic gene expression.bioRxiv : the preprint server for biology · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Chromatin: the old and young of it.Frontiers in molecular biosciences · 2023
    Review
  19. Hand Dissection of Caenorhabditis elegans Intestines.Journal of visualized experiments : JoVE · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Timothy J DurhamDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.ORCID 0000-0003-2056-4199
Riza M DazaDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.
Louis GevirtzmanDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.
Darren A CusanovichDepartment of Cellular and Molecular Medicine, University of Arizona, Tucson, Arizona 85721, USA.ORCID 0000-0001-6889-0095
Olubusayo BolonduroDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.ORCID 0000-0001-9473-2648
William Stafford NobleDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.ORCID 0000-0001-7283-4715
Jay ShendureDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.ORCID 0000-0002-1516-1865
Robert H WaterstonDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.ORCID 0000-0001-5956-5215
University of Washington · USHoward Hughes Medical Institute · USUniversity of Arizona · US

Funding

Resource ProjectU41HG007355 · NHGRI · UNIVERSITY OF WASHINGTON · PI WATERSTON, ROBERT H · 2013 to 2021
$20.8M
Automated single-cell expression analysis in C. elegansR01GM072675 · NIGMS · UNIVERSITY OF WASHINGTON · PI WATERSTON, ROBERT H · 2005 to 2017
$7.1M
Diversity Action Plan: UW GenOM ProjectR25HG007153 · NHGRI · UNIVERSITY OF WASHINGTON · PI EICHLER, EVAN · 2013 to 2020
$2.3M
Gene expression and regulation in C. elegans with single cell resolutionR01HG010478 · NHGRI · UNIVERSITY OF WASHINGTON · PI WATERSTON, ROBERT H · 2019 to 2021
$1.5M
NHGRI NIH HHS R01 HG010478NHGRI NIH HHS R25 HG007153NHGRI NIH HHS U41 HG007355NIGMS NIH HHS R01 GM072675
6 · The paper itself

Abstract

Recently developed single-cell technologies allow researchers to characterize cell states at ever greater resolution and scale.

Indexed as

Caenorhabditis elegansChromatinAnimalsChromatin Immunoprecipitation SequencingDNAGene Expression RegulationChromatinDNA

Identifiers

PMID33888511
PMCPMC8494234
OpenAlexW3154376322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.