Evidence map›Paper›PMID 33888417›Full record

ArticleCardiovascular revascularization medicine : including molecular interventions2022

Index Admission and Thirty-Day Readmission Outcomes of Patients With Cancer Presenting With STEMI.

Mohammed Osman, Mina M Benjamin, Sudarshan Balla, Babikir Kheiri, Christopher Bianco, Partho P Sengupta, Ramesh Daggubati, Midhun Malla, Stephen V Liu, Mamas Mamas and 1 more

Open access · greenAbstract read
In one paragraph

Article in Cardiovascular revascularization medicine : including molecular interventions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Mohammed OsmanDivision of Cardiology, West Virginia University School of Medicine, Morgantown, WV, USA.
Mina M BenjaminDivision of Cardiology, West Virginia University School of Medicine, Morgantown, WV, USA.
Sudarshan BallaDivision of Cardiology, West Virginia University School of Medicine, Morgantown, WV, USA.
Babikir KheiriKnight Cardiovascular Institute, Oregon Health and Science University, Portland, OR, USA.
Christopher BiancoDivision of Cardiology, West Virginia University School of Medicine, Morgantown, WV, USA.
Partho P SenguptaDivision of Cardiology, West Virginia University School of Medicine, Morgantown, WV, USA.
Ramesh DaggubatiDivision of Cardiology, West Virginia University School of Medicine, Morgantown, WV, USA.
Midhun MallaDivision of Oncology, West Virginia University, School of Medicine, Morgantown, WV, USA.
Stephen V LiuDivision of Oncology, Medstar Georgetown University Hospital, Washington, DC, USA.
Mamas MamasKeele Cardiovascular Research Group, Keele University, Keele, United Kingdom; Royal Stoke University Hospital, Stoke-on-Trent, United Kingdom.
Brijesh PatelDivision of Cardiology, West Virginia University School of Medicine, Morgantown, WV, USA. Electronic address: brijesh.patel@wvumedicine.org.
West Virginia University · USMedStar Georgetown University Hospital · USOregon Health & Science University · USRoyal Stoke University Hospital · GB

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

backgroundNational-level data of cancer patients' readmissions after ST-segment elevation myocardial infarction (STEMI) are lacking.

objectivesThe primary aim of this study was to compare the rates and causes of 30-day readmissions in patients with and without cancer.

methodsAmong patients admitted with STEMI in the United States National Readmission Database (NRD) from October 2015-December 2017, we identified patients with the diagnosis of active breast, colorectal, lung, or prostate cancer. The primary endpoint was the 30-day unplanned readmission rate. Secondary endpoints included in-hospital outcomes during the index admission and causes of readmissions. A propensity score model was used to compare the outcomes of patients with and without cancer.

resultsA total of 385,522 patients were included in the analysis: 5956 with cancer and 379,566 without cancer. After propensity score matching, 23,880 patients were compared (Cancer = 5949, No Cancer = 17,931). Patients with cancer had higher 30-day readmission rates (19% vs. 14%, p < 0.01). The most common causes for readmission among patients with cancer were cardiac (31%), infectious (21%), oncologic (17%), respiratory (4%), stroke (4%), and renal (3%). During the first readmission, patients with cancer had higher adjusted rates of in-hospital mortality (15% vs. 7%; p < 0.01) and bleeding complications (31% vs. 21%; p < 0.01), compared to the non-cancer group. In addition, cancer (OR 1.5, 95% CI 1.2-1.6, p < 0.01) was an independent predictor for 30-day readmission.

conclusionsAbout one in five cancer patients presenting with STEMI will be readmitted within 30 days. Cardiac causes predominated the reason for 30-day readmissions in patients with cancer.

Indexed as

NeoplasmsST Elevation Myocardial InfarctionDatabases, FactualHospitalizationHospital MortalityHumansMalePatient ReadmissionRetrospective StudiesRisk FactorsUnited States30-day outcomesCancerIn-hospital outcomesST-segment elevation myocardial infarction

Identifiers

PMID33888417
PMCPMC8521583
OpenAlexW3153562547

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.