Evidence map›Paper›PMID 33888081›Full record

SynthesisBMC nephrology2021

Modifiable risk factors of acute kidney injury after liver transplantation: a systematic review and meta-analysis.

Jian Zhou, Xueying Zhang, Lin Lyu, Xiaojun Ma, Guishen Miao, Haichen Chu

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  13. The Effect of Perioperative Fluid Therapy on Postoperative Renal Functions in Patients Receiving Liver Transplantation from Living Donors: A Retrospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  14. Article
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  16. Intraoperative kidney replacement therapy in acute liver failure.Pediatric nephrology (Berlin, Germany) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jian ZhouDepartment of Anesthesiology, The Affiliated Hospital of Qingdao University, School of Clinical Medicine, Qingdao University, No. 59, Haier Road, Qingdao, 266100, Shandong Province, China.
Xueying ZhangDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610000, Sichuan Province, China.
Lin LyuDepartment of Anesthesiology, The Affiliated Hospital of Qingdao University, School of Clinical Medicine, Qingdao University, No. 59, Haier Road, Qingdao, 266100, Shandong Province, China.
Xiaojun MaDepartment of Anesthesiology, The Affiliated Hospital of Qingdao University, School of Clinical Medicine, Qingdao University, No. 59, Haier Road, Qingdao, 266100, Shandong Province, China.
Guishen MiaoDepartment of Anesthesiology, The Affiliated Hospital of Qingdao University, School of Clinical Medicine, Qingdao University, No. 59, Haier Road, Qingdao, 266100, Shandong Province, China.
Haichen ChuDepartment of Anesthesiology, The Affiliated Hospital of Qingdao University, School of Clinical Medicine, Qingdao University, No. 59, Haier Road, Qingdao, 266100, Shandong Province, China. chiefchu@126.com.
Affiliated Hospital of Qingdao University · CNQingdao University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is a common and critical complication of liver transplantation (LT), which is associated with increased morbidity, mortality and health care cost. We aimed to identify modifiable risk factors of AKI after LT.

methodsA literature search of Pubmed, EMBASE and Cochrane Databases was performed to identify studies investigating risk factors of AKI after LT. The Newcastle-Ottawa Scale was used to rate study quality. Effect size and 95% confidence interval were pooled using a random-effect model with inverse-variance method.

resultsSixty-seven articles with 28,844 patients were included in the meta-analysis. Seventeen modifiable risk factors were found, including overweight, preoperative use of diuretic, preoperative anemia, donation after cardiac death organ, donor BMI ≥ 30 kg/m

conclusionsEffective interventions based on identified modifiable risk factors in the perioperative management and graft allocation and preservation may be promising to reduce the incidence of AKI after LT.

trial registrationThe protocol for this systematic review is registered with PROSPERO (No. CRD42020166918 ).

Indexed as

Acute Kidney InjuryHumansIntraoperative ComplicationsLiver TransplantationPostoperative ComplicationsRisk FactorsTissue DonorsAcute kidney injuryLiver transplantationMeta-analysisModifiable risk factors

Identifiers

PMID33888081
PMCPMC8063403
OpenAlexW3153868381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.