Evidence map›Paper›PMID 33888063›Full record

ArticleBMC pediatrics2021

Epidemiological and virological characteristics of respiratory tract infections in children during COVID-19 outbreak.

Yueling Zhu, Wei Li, Binbin Yang, Ruiying Qian, Fang Wu, Xue He, Qinheng Zhu, Jinling Liu, Yan Ni, Jianbing Wang and 1 more

Abstract read
In one paragraph

Article in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yueling Zhu *Department of Traditional Chinese Medicine, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, 310052, Hangzhou, Zhejiang Province, PR China.
Wei Li *Department of Clinical Laboratory, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, 310052, Hangzhou, Zhejiang Province, PR China.
Binbin YangDepartment of General Surgery, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, 310052, Hangzhou, Zhejiang Province, PR China.
Ruiying QianDepartment of Neurology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, 3333 Binsheng road, Zhejiang Province, 310052, Hangzhou, PR China.
Fang WuDepartment of Traditional Chinese Medicine, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, 310052, Hangzhou, Zhejiang Province, PR China.
Xue HeDepartment of Nephrology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, 310052, Hangzhou, Zhejiang Province, PR China.
Qinheng ZhuDepartment of Public Health, Zhejiang University School of Medicine, 310058, Hangzhou, Zhejiang Province, PR China.
Jinling LiuDepartment of Pulmonology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, 310052, Hangzhou, Zhejiang Province, PR China.
Yan NiDepartment of Clinical Laboratory, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, 310052, Hangzhou, Zhejiang Province, PR China.
Jianbing WangDepartment of Epidemiology and Biostatistics, The Children's Hospital, National Clinical Research Center for Child Health, Zhejiang University School of Medicine, , 310058, Hangzhou, Zhejiang Province, PR China.
Shanshan MaoDepartment of Neurology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, 3333 Binsheng road, Zhejiang Province, 310052, Hangzhou, PR China. 6307003@zju.edu.cn.ORCID 0000-0001-6736-1407

Funding

National Natural Science Foundation of China 81801490
6 · The paper itself

Abstract

backgroundTo investigate the impact of protective measures and isolation on respiratory tract infections in children during the COVID-19 outbreak.

methodsWe extracted data on outpatient visits and respiratory infection visits, and tests of respiratory viruses (adenovirus (ADV), influenza A (FluA), influenza B (FluB) and respiratory syncytial virus (RSV)) from electronic healthcare records in Children's Hospital, Zhejiang University School of Medicine during the COVID-19 outbreak (January-April, 2020), compared with those in 2018 and 2019 during the same periods.

resultsWe found that outpatient visits in January, 2020 was comparable with those in 2018 and 2019, but decreased by 59.9% (288,003 vs. 717,983) and 57.4% (288,003 vs. 676,704), respectively during the period of February-April, 2020, as compared with the same periods in 2018 and 2019. The total number of respiratory tract infections from January to April 2020 decreased by 65.7% (119,532 vs.348,762) and 59.0% (119,532 vs.291,557), respectively compared with the same periods in 2018 and 2019. The proportion of respiratory tract infections during the outbreak also dropped compared with the same periods in 2018 and 2019 (P<0.001). We also found significantly decreased number of completed tests for respiratory viruses and positive cases of ADV, FluA, FluB, and RSV during February-April, 2020.

conclusionsIn this study, we found that outpatient visits and respiratory tract infections in children significantly decreased during COVID-19 outbreak. Adequate protective measures and isolation in children may help to prevent respiratory virus infections in children.

Indexed as

COVID-19Respiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsChildDisease OutbreaksHumansInfantSARS-CoV-2ChildrenCOVID-19Epidemiological characteristicsOutpatient visitsRespiratory tract infection

Identifiers

PMID33888063
PMCPMC8060686

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.