Evidence map›Paper›PMID 33887985›Full record

SynthesisThe Journal of international medical research2021

Efficacy and safety of radiofrequency ablation for treatment of knee osteoarthritis: a meta-analysis of randomized controlled trials.

Hua Zhang, Bo Wang, Jie He, Zhongju Du

2 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05283889 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

The Safety and Efficacy of Genicular Radiofrequency Ablation for Patients With Persistent Knee Pain Following Total Knee Arthroplasty - A Triple Blinded Randomized Sham-Controlled Trial

TypeinterventionalSponsorUniversity of CalgaryRan2022 to 2026Enrolled44ConditionsOsteoarthritis, KneeArmsGenicular Radiofrequency Ablation, Sham Genicular Radiofrequency Ablation
NCT05962463 recruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of the Effectiveness of Pulsed Radiofrequency Therapy and Canal Adductor Blockade for Chronic Pain and Functioning in Knee Osteoarthritis

TypeobservationalSponsorUniversity Medical Centre LjubljanaRan2024 to 2025Enrolled128ConditionsKnee OsteoarthritisArmsCanal adductor blockade, Canal adductor pulsed radio-frequency therapy
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  17. Treatment Options for Patellofemoral Arthritis.Current reviews in musculoskeletal medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hua ZhangDepartment of Anesthesiology and Pain Management, The Third People's Hospital of Hangzhou, Hangzhou, Zhejiang, China.
Bo WangDepartment of Anesthesiology and Pain Management, The Third People's Hospital of Hangzhou, Hangzhou, Zhejiang, China.
Jie HeDepartment of Anesthesiology and Pain Management, The Third People's Hospital of Hangzhou, Hangzhou, Zhejiang, China.
Zhongju DuDepartment of Anesthesiology and Pain Management, The Third People's Hospital of Hangzhou, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0000-0003-4586-6169
Third People's Hospital of Hangzhou · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the efficacy and safety of radiofrequency ablation for the treatment of knee osteoarthritis.

methodsA literature review was conducted using the PubMed, Cochrane Review, Embase, and Google Scholar databases. Two reviewers independently assessed the eligibility of all retrieved studies. The research was reported based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to ensure the reliability and verity of the results. The statistical analysis was performed using STATA version 13.0.

resultsNine randomized controlled trials were collected for the data extraction and meta-analysis. Significant differences in the pain score at 4, 12, and 24 weeks were found between patients treated with radiofrequency ablation and those treated with placebo. Furthermore, the use of radiofrequency ablation was associated with an improved outcome of the Western Ontario and McMaster Universities Arthritis Index at 4, 12, and 24 weeks. No serious adverse events were observed in any patients who underwent radiofrequency ablation.

conclusionRadiofrequency ablation is efficacious and safe for reducing pain and improving knee function in patients with knee osteoarthritis, without increasing the risk of adverse effects.

Indexed as

Osteoarthritis, KneeRadiofrequency AblationHumansKnee JointRandomized Controlled Trials as TopicReproducibility of ResultsTreatment Outcomeadverse eventknee functionKnee osteoarthritismeta-analysispainradiofrequency ablation

Identifiers

PMID33887985
PMCPMC8072859
OpenAlexW3156754146

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.