Evidence map›Paper›PMID 33887886›Full record

ReviewZhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns2021

[Research advances on the mechanism of fractional laser in treating scars].

H Z Liu, K Y Lyu

Open access · greenAbstract readReview
In one paragraph

Review in Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

H Z LiuDepartment of Plastic Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
K Y LyuDepartment of Plastic Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
XinHua Hospital · CN

Funding

Clinical Research Plan of Shanghai Hospital Development Center SHDC2020CR3039BGeneral Program of National Natural Science Foundation of China 81772091
6 · The paper itself

Abstract

Scars are the result of abnormal repair of skin tissue trauma. Recently, fractional laser is more and more widely used in the treatment of scars, but its mechanism is not clear. Studies have shown that fractional laser could produce multiple microthermal zones in target skin, induce wound repair responses, affect the function of epidermal and dermal cells, induce changes in blood vessels and collagens, and change the expression of heat shock proteins, microRNA, matrix metalloproteinases, cytokines such as transforming growth factor β, basic fibroblast growth factor, and facilitate drug delivery, thus achieving the effect of treating scars. This article reviews the mechanism of fractional laser in treating scars from three aspects, including the tissue and cell mechanism, molecular mechanism, and drug delivery.

Indexed as

CicatrixLasers, GasDrug Delivery SystemsHumansSkin

Identifiers

PMID33887886
PMCPMC11917304
OpenAlexW3155833612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.