ArticleUltrasonography (Seoul, Korea)2021
Contrast-enhanced voiding urosonography for the diagnosis of vesicoureteral reflux and intrarenal reflux: a comparison of diagnostic performance with fluoroscopic voiding cystourethrography.
Article in Ultrasonography (Seoul, Korea), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Determining the optimal contrast-enhanced voiding urosonography technique for vesicoureteral reflux in children and adolescents: a systematic review and network meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Renal volumetry and functional impairment prediction in pediatric vesicoureteral reflux based on contrast-enhanced voiding urosonography.Quantitative imaging in medicine and surgery · 2026Article
- Diagnostic performance of contrast-enhanced voiding ultrasonography and direct radionuclide cystography with physiologic bladder filling volumes in pediatric vesicoureteral reflux-a prospective study.European journal of pediatrics · 2026Article
- Intrarenal reflux is linked to subsequent kidney scarring: a retrospective study.Pediatric nephrology (Berlin, Germany) · 2025Article
- Expanding Role of Contrast-Enhanced Ultrasound and Elastography in the Evaluation of Abdominal Pathologies in Children.Diagnostics (Basel, Switzerland) · 2025Review
- What paediatricians need to know about modern urologic management of vesicoureteral reflux.Frontiers in pediatrics · 2025Review
- Review
- Reduced kidney size and renal function of high-grade vesicoureteral reflux and intrarenal reflux in contrast-enhanced voiding urosonography.Frontiers in pediatrics · 2024Article
- Prevalence of intrarenal reflux in pediatric patients on contrast-enhanced voiding urosonography.Pediatric radiology · 2023Article
- A narrative review on the applications of intracavitary contrast-enhanced ultrasonography in pediatric lower genitourinary anomalies.Frontiers in pediatrics · 2023Review
- Application of urodynamics combined with contrast-enhanced ultrasound in evaluation of the urinary tract in patients with low bladder compliance and vesicoureteric reflux who underwent bladder augmentation alone.The Kaohsiung journal of medical sciences · 2022Article
- Contrast-enhanced voiding ultrasonography to detect intrarenal reflux in children: comparison with 99mTc-DMSA renal scans.Ultrasonography (Seoul, Korea) · 2022Article
- The Spectrum of Parenchymal Changes in Kidneys Affected by Intrarenal Reflux, Diagnosed by Contrast-Enhanced Voiding Urosonography and DMSA Scan.Frontiers in pediatrics · 2022Article
- Contrast-enhanced ultrasound: a comprehensive review of safety in children.Pediatric radiology · 2021Review
- Comparison of voiding vesicoureteral urosonography with fluoroscopic voiding cystourethrography in children with vesicoureteral reflux.Pakistan journal of medical sciencesArticle
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9 authors.
Funding
Abstract
purposeThis study evaluated the diagnostic performance of contrast-enhanced voiding urosonography (ce-VUS) using a second-generation ultrasound contrast agent for the diagnosis of vesicoureteral reflux (VUR) and intrarenal reflux (IRR), and compared it with that of standard fluoroscopic voiding cystourethrography (VCUG).
methodsThirty-two consecutive children from April to October 2019 were included in this study. ce-VUS and VCUG were performed simultaneously by two operators with intravesical infusion of a mixture of ultrasound contrast medium, iodinated contrast medium and water. Two pediatric radiologists independently reviewed the ce-VUS and VCUG images and reported the presence and degree of VUR (grades I-V), and the presence and type of IRR.
resultsTwenty-seven of 63 urinary systems showed VUR. Interobserver agreement for VUR grading was very good for both examinations (κ=0.87; 95% confidence interval [CI], 0.82 to 0.92 for ce-VUS and κ=0.92; 95% CI, 0.87 to 0.96 for VCUG). The detection rate of VUR showed no significant difference between the two examinations (P=0.370). Four cases of VUR were missed on ce-VUS, while one case of VUR was missed on VCUG. All four false-negative cases on ce-VUS were grade 1 VUR. The two examinations showed very good agreement regarding VUR grading (κ =0.89; 95% CI, 0.81 to 0.96). IRR was more frequently detected with ce-VUS than with VCUG (10 cases with ce-VUS vs. 3 cases with VCUG, P=0.016).
conclusionce-VUS showed very good agreement with VCUG for detecting grade 2 VUR and above, while grade 1 VUR was sometimes missed with ce-VUS. IRR was more frequently detected with ce-VUS than with VCUG.
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