Evidence map›Paper›PMID 33887435›Full record

ArticleFree radical biology & medicine2021

Suppression of mitochondrial respiration by hydrogen sulfide in hibernating 13-lined ground squirrels.

Birgitte S Jensen, Sibile Pardue, Brynne Duffy, Christopher G Kevil, James F Staples, Angela Fago

Open access · hybridAbstract read
In one paragraph

Article in Free radical biology & medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Mechanisms of Protection Against Oxidative Stress During Hibernation.International journal of molecular sciences · 2026
    Review
  3. Power and poison: The intersections of HThe Journal of biological chemistry · 2025
    Review
  4. Silencing of ultradian rhythms and metabolic depression during spontaneous daily torpor in Djungarian hamsters.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024
    Article
  5. Sulfide catabolism in hibernation and neuroprotection.Nitric oxide : biology and chemistry · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Birgitte S JensenDepartment of Biology, Aarhus University, Aarhus C, 8000, Denmark; Department of Biology, University of Western Ontario, London, ON N6A 5B8, Canada.
Sibile PardueDepartment of Pathology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Brynne DuffyDepartment of Biology, University of Western Ontario, London, ON N6A 5B8, Canada.
Christopher G KevilDepartment of Pathology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
James F StaplesDepartment of Biology, University of Western Ontario, London, ON N6A 5B8, Canada.
Angela FagoDepartment of Biology, Aarhus University, Aarhus C, 8000, Denmark. Electronic address: angela.fago@bio.au.dk.
Western University · CALouisiana State University Health Sciences Center Shreveport · USAarhus University · DK

Funding

Stress Exacerbates Myocardial Ischemic Injury by Blocking Estrogen's Antidoxidant Protection in the Female HeartP20GM121307 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI Vesna Tesic · 2018 to 2026
$23.6M
CSE regulation of vascular remodelingR01HL149264 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI KEVIL, CHRISTOPHER G · 2020 to 2023
$1.7M
NHLBI NIH HHS R01 HL149264NIGMS NIH HHS P20 GM121307
6 · The paper itself

Abstract

Hibernating mammals may suppress their basal metabolic rate during torpor by up to 95% to reduce energy expenditure during winter, but the underlying mechanisms remain poorly understood. Here we show that hydrogen sulfide (H

Indexed as

HibernationHydrogen SulfideAnimalsMitochondriaRespirationSciuridaeHydrogen SulfideH(2)SHypometabolismIctidomys tridecemlineatussulfide:quinone oxidoreductaseTorpor

Identifiers

PMID33887435
PMCPMC8809085
OpenAlexW3156549881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.