Evidence map›Paper›PMID 33887193›Full record

ArticleNeuron2021

Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience.

Helen Rankin Willsey, Cameron R T Exner, Yuxiao Xu, Amanda Everitt, Nawei Sun, Belinda Wang, Jeanselle Dea, Galina Schmunk, Yefim Zaltsman, Nia Teerikorpi and 8 more

Abstract readPublished Erratum
In one paragraph

Article in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Pharmaco-behavioral profiling identifies suppressors of autism gene-associated phenotypes in zebrafish.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Human-specific gene expansions contribute to brain evolution.bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. The chromatin remodeler ADNP regulates neurodevelopmental disorder risk genes and neocortical neurogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Context-dependent hyperactivity inFrontiers in molecular neuroscience · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Helen Rankin Willsey
Cameron R T Exner
Yuxiao Xu
Amanda Everitt
Nawei Sun
Belinda Wang
Jeanselle Dea
Galina Schmunk
Yefim Zaltsman
Nia Teerikorpi
Albert Kim
Aoife S Anderson
David Shin
Meghan Seyler
Tomasz J Nowakowski
Richard M Harland
A Jeremy Willsey
Matthew W State

Funding

The Psychiatric Cell Map Initiative: Connecting Genomics, Subcellular Networks, and Higher Order PhenotypesU01MH115747 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KAMPMANN, MARTIN, KROGAN, NEVAN J · 2018 to 2022
$19.6M
Gene Expression in Amphibian DevlopementR01GM042341 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARLAND, RICHARD M · 1988 to 2016
$5.7M
TRAINING THE NEXT GENERATION OF MENTAL HEALTH RESEARCHERSR25MH060482 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DANIEL H MATHALON, Susan M. Voglmaier · 2000 to 2026
$5.2M
Gene Expression in Amphibian DevelopmentR35GM127069 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Richard M Harland · 2018 to 2026
$4.2M
Identifying phenotypic convergence among autism spectrum disorder (ASD) genes using CRISPR/Cas9 in XenopusR21MH112158 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARLAND, RICHARD M · 2017 to 2018
$417k
NIGMS NIH HHS R01 GM042341NIGMS NIH HHS R35 GM127069NIMH NIH HHS R21 MH112158NIMH NIH HHS R25 MH060482NIMH NIH HHS U01 MH115747
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID33887193
PMCPMC8145999

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.