ArticleNeuron2021
SexX matters when it comes to pain.
Article in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Sexual Dimorphism of Inputs to the Lateral Habenula in Mice.Neuroscience bulletin · 2022Article
- Reprogramming the topology of the nociceptive circuit in C. elegans reshapes sexual behavior.Current biology : CB · 2022Article
- The neglect of sex: A call to action for including sex as a biological variable in placebo and nocebo research.Contemporary clinical trials · 2022Review
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neurobiology of sex differences in pain remain poorly understood. Yu et al. (2021) provide new insight by demonstrating that activation of dopaminergic projections from PAG to BNST provides substantial pain relief in male mice but virtually none in females.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.