ArticleACS chemical biology2021
Site-Specific Lipidation Enhances IFITM3 Membrane Interactions and Antiviral Activity.
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Article in ACS chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29citing papers in PubMed
–field-weighted citation impact
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed.
- S-palmitoylation of the v-ATPase subunit RNAseK is necessary for Zika virus infection.Virology journal · 2026Article
- Genetically encoded green-light-responsive photocaged lysine for sequential control of protein function.Chemical science · 2026Article
- IFITM3 at the viral fusion-pore checkpoint: membrane energetics and entry-route-dependent outcomes.Frontiers in immunology · 2026Review
- S-palmitoylation and depalmitoylation at the interface of animal virus-host interactions.Frontiers in cellular and infection microbiology · 2026Review
- Protein S-Palmitoylation as Potential Therapeutic Target for Dermatoses.Biomolecules · 2025Review
- Review
- Protein lipidation in the tumor microenvironment: enzymology, signaling pathways, and therapeutics.Molecular cancer · 2025Review
- IFITM1 is a host restriction factor that inhibits porcine epidemic diarrhea virus infection.Journal of nanobiotechnology · 2024Article
- Engineering Pyrrolysine Systems for Genetic Code Expansion and Reprogramming.Chemical reviews · 2024Review
- The Antiviral Activity of Interferon-Induced Transmembrane Proteins and Virus Evasion Strategies.Viruses · 2024Review
- Orthogonal Translation for Site-Specific Installation of Post-translational Modifications.Chemical reviews · 2024Review
- Role of Viral Envelope Proteins in Determining Susceptibility of Viruses to IFITM Proteins.Viruses · 2024Review
- Discovery and Characterization of IFITMViruses · 2023Review
- One-step site-specific S-alkylation of full-length caveolin-1: Lipidation modulates the topology of its C-terminal domain.Protein science : a publication of the Protein Society · 2023Article
- S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy.Molecular cell · 2023Article
- Functional analysis of protein post-translational modifications using genetic codon expansion.Protein science : a publication of the Protein Society · 2023Review
- The Art of Viral Membrane Fusion and Penetration.Sub-cellular biochemistry · 2023Article
- ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins.mBio · 2022Article
- Interferon-induced transmembrane protein 3 (IFITM3) and its antiviral activity.Current opinion in structural biology · 2022Review
- Instability Challenges and Stabilization Strategies of Pharmaceutical Proteins.Pharmaceutics · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Emma H GarstLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.ORCID 0000-0001-8170-2343
Hwayoung LeeDepartment of Biological Sciences, Chemistry, and Bioengineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States.ORCID 0000-0003-2332-1993
Tandrila DasLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.
Shibani BhattacharyaNew York Structural Biology Center, New York, New York 10027, United States.
Avital PercherLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.
Rafal WiewioraTri-Institutional Ph.D. Program in Chemical Biology, New York, New York 10065, United States.ORCID 0000-0002-8961-7183
Isaac P WitteLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.
Yumeng LiState Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China.
Tao PengState Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China.ORCID 0000-0002-5578-5314
Wonpil ImDepartment of Biological Sciences, Chemistry, and Bioengineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States.ORCID 0000-0001-5642-6041
Howard C HangLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.ORCID 0000-0003-4053-5547
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M900 MHz NMR Spectrometer for Structural BiologyP41GM066354 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI COWBURN, DAVID · 2002 to 2006
$4.7MStudies on Protein LipidationR01GM087544 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI HANG, HOWARD C · 2010 to 2023
$4.4MEXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR015495 · NCRR · NEW YORK STRUCTURAL BIOLOGY CENTER · PI RIFKIND, RICHARD A · 2000 to 2000
$2.0MTri-Institutional PhD Program in Chemical BiologyT32GM115327 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI TAN, DEREK S · 2015 to 2019
$741kDistal gut microbiome targets of host anti-proteolytic proteins during colitisR21AI156674 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI HANG, HOWARD C · 2021 to 2022
$488kNCI NIH HHS P30 CA008748NCRR NIH HHS C06 RR015495NIAID NIH HHS R21 AI156674NIGMS NIH HHS P41 GM066354NIGMS NIH HHS R01 GM087544NIGMS NIH HHS T32 GM115327
Abstract
Interferon-induced transmembrane proteins (IFITMs) are
Indexed as
Amino Acid SequenceAntiviral AgentsBinding SitesCell MembraneComputational BiologyDrug DesignHumansInterferonsLipidsLipoylationLysosomesMembrane ProteinsMolecular Dynamics SimulationProtein BindingProtein ConformationRNA-Binding ProteinsAntiviral AgentsIFITM3 protein, humanInterferonsLipidsMembrane ProteinsRNA-Binding Proteins
Identifiers
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.