Evidence map›Paper›PMID 33887119›Full record

ArticleUnited European gastroenterology journal2021

Transabdominal ultrasonography to reduce the burden of X-ray imaging in prophylactic pancreatic stent localization after ERCP-A prospective trial.

Florian Alexander Michael, Ludmilla Gerber, Nina Weiler, Peter Marton Hunyady, Nada Abedin, Anna-Lena Laguna de la Vera, Philipp Stoffers, Natalie Filmann, Stefan Zeuzem, Jörg Bojunga and 2 more

Open access · hybridAbstract read
In one paragraph

Article in United European gastroenterology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Florian Alexander MichaelDepartment of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.ORCID 0000-0002-9305-3691
Ludmilla GerberDepartment of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.
Nina WeilerDepartment of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.
Peter Marton HunyadyDepartment of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.
Nada AbedinDepartment of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.
Anna-Lena Laguna de la VeraDepartment of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.
Philipp StoffersDepartment of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.
Natalie FilmannInstitute of Biostatistics and Mathematical Modeling, Frankfurt, Germany.
Stefan ZeuzemDepartment of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.
Jörg BojungaDepartment of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.
Mireen Friedrich-RustDepartment of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.
Georg DultzDepartment of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.ORCID 0000-0003-0775-0907
Goethe University Frankfurt · DEInstitute of Mathematics and Mathematical Modeling · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBefore performing endoscopy to remove prophylactic pancreatic stents placed in patients with high risk of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP), X-ray imaging is recommended to confirm the stents position in the pancreatic duct.

objectivesThe aim of the present study was to investigate the feasibility of prophylactic pancreatic stent detection by transabdominal ultrasonography, to reduce the burden of X-ray imaging, which is currently the golden standard.

methodsAll patients who received a pancreatic stent for PEP prophylaxis were included in the present prospective trial. First, stent position was determined by transabdominal ultrasonography. Afterwards, it was verified by X-ray imaging. Retained stents were removed by esophagogastroduodenoscopy. Dislocated stents needed no further intervention.

resultsFourty-one patients were enrolled in this study. All prophylactic pancreatic stents were straight 6 cm long 5 Fr stents with external flap. All stents were removed between day 1 and 10 (median: 3 days) in all cases. In 34 of 41 cases (83.0%), the pancreatic stent was still in place on the day of examination. Twenty-nine of 34 (85.3%) stents were detected correctly by transabdominal ultrasonography. Overlying gas prevented visualization of the pancreas in 3/41 (7.3%) cases. Sensitivity of sonographic detection of the stent was 93.5% (29/31). Six of seven stents were determined correctly as dislocated by ultrasonography. Here, specificity was 85.7%. A positive predictive value of 96.7% (29/30) was examined. The negative predictive value was 75.0% (6/8).

conclusionTransabdominal ultrasonography detects the majority of prophylactic pancreatic stents. Thereby, it helps to identify patients with an indication for endoscopy sufficiently. X-ray imaging could subsequently be omitted in about 70% of examinations, reducing the radiation exposure for the patient and the endoscopy staff.

Indexed as

Device RemovalStentsAdultAgedAged, 80 and overCholangiopancreatography, Endoscopic RetrogradeFeasibility StudiesFemaleHumansIntention to Treat AnalysisMaleMiddle AgedPancreatic DuctsPancreatitisPostoperative ComplicationsProspective Studiesendoscopic retrograde cholangiopancreatographyendoscopypancreatitisprophylactic pancreatic stenttransabdominalX-ray imaging

Identifiers

PMID33887119
PMCPMC8259253
OpenAlexW3156376060

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.