ArticleArquivos brasileiros de cardiologia2021
Statins Prescriptions and Lipid Levels in a Tertiary Public Hospital.
Article in Arquivos brasileiros de cardiologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 3 citations in OpenAlex.
- Brazilian Guideline on Dyslipidemias and Prevention of Atherosclerosis - 2025.Arquivos brasileiros de cardiologia · 2025Article
- Achieving LDL-Cholesterol Goals: Can Implementation Science Save Us?Arquivos brasileiros de cardiologia · 2025Article
- Cardiovascular risk and statin prescription in primary care: an observational study, São Leopoldo, 2018-2021.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Observational
- Estimate of Brazilians Under Secondary Prevention of Cardiovascular Events Who Do Not Achieve LDL Cholesterol Targets with Lipid-Lowering Therapy.Arquivos brasileiros de cardiologia · 2025Article
- Chronic Coronary Syndrome In Brazil: We Need To Know More.Arquivos brasileiros de cardiologia · 2023Article
- Achievement of LDL-cholesterol Targets: Why do We Fail, and How Can We Improve?Arquivos brasileiros de cardiologia · 2022Article
- Statin Use and Hypercholesterolemia: Are the Current Guidelines' Recommendations Being Followed?Arquivos brasileiros de cardiologia · 2021Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe development of a new class of medications that are highly capable of reducing LDL-cholesterol renewed the interest in the characterization of familial hypercholesterolemia patients. Nevertheless, little is known about the lipid profile of patients in tertiary healthcare centers in Brazil in order to better estimate the real occurrence of familial hypercholesterolemia, with initial suspect of LDL-cholesterol levels above 190 mg/d/L.
objectivesThis study evaluated the lipid profile (total cholesterol and LDL-cholesterol) in ambulatory patients from a general tertiary public hospital.
methodsRetrospective study comparing prescriptions of statins and lipid profile results. The significance level was established in 5%.
resultsIn one year, 9,594 individuals received statin prescriptions, of whom 51.5% were females and the mean age was 63.7±12.9 years-old (18 to 100 years-old). Thirty-two medical specialties prescribed statins. Cardiology was responsible for 43% of the total. Nearly 15% of those patients with a prescription did not have a recent total cholesterol result and 1,746 (18%) did not have a recent LDL-cholesterol measurement. The occurrence of the latter between 130 and 190 mg/dL was present in 1,643 (17.1%) individuals, and 228 (2.4%) patients had an LDL-cholesterol ≥190mg/dL among those using statins at distinct doses. Only two statins were used: simvastatin and atorvastatin. The first was prescribed in 77.6% of the prescriptions.
conclusionIn this cross-sectional cohort at a tertiary general hospital, statins have been widely prescribed but with little success in achieving recognized levels of control. There is probably a significant number of FH individuals in this cohort that need to be properly diagnosed in order to receive adequate treatment due to its prognostic implications.
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