Evidence map›Paper›PMID 33886663›Full record

ArticlePloS one2021

Clinical characteristics and outcomes of patients with Corona Virus Disease 2019 (COVID-19) at Mercy Health Hospitals, Toledo, Ohio.

Muhammad Shayan Khan, Ratika Dogra, Leela K V Miriyala, F N U Salman, Rizwan Ishtiaq, Dilnoor K Patti, Aakash Kumar, Gaurav Sandho, Karim Jacob, Kritika Luthra and 10 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 4 pooled it
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Mental and social burden of COVID-19 on the Iraqi people.The International journal of social psychiatry · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 1 institution in 1 country.

Muhammad Shayan KhanInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.ORCID 0000-0002-2888-1191
Ratika DograInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Leela K V MiriyalaInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
F N U SalmanInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Rizwan IshtiaqInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Dilnoor K PattiInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Aakash KumarInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Gaurav SandhoInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Karim JacobInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Kritika LuthraInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Ravina SharmaInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Rekha RavikumarInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Dharmakaruna EdaraInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Shanti PittampalliInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Divya SoodInternal Medicine Residency, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Vinod KhatriPulmonary and Critical Care, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Vijay MahajanPulmonary and Critical Care, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Salil AvasthiPulmonary and Critical Care, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.ORCID 0000-0002-4609-6656
Arlette AuoadInfectious Diseases, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Srinivas KatragaddaPulmonary and Critical Care, Mercy St Vincent Medical Centre, Toledo, Ohio, United States of America.
Mercy St. Vincent Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceThe ongoing pandemic of the novel Corona Virus Disease 2019 (COVID-19) is an unprecedented challenge to global health, never experienced before.

objectiveThis study aims to describe the clinical characteristics and outcomes of patients with COVID-19 admitted to Mercy Hospitals. DESIGN AND

methodsRetrospective, observational cohort study designed to include every COVID-19 subject aged 18 years or older admitted to Mercy Saint (St) Vincent, Mercy St Charles, and Mercy St Anne's hospital in Toledo, Ohio from January 1, 2020 through June 15th, 2020. Primary Outcome Measure was mortality in the emergency department or as an in-patient.

results470 subjects including 224 males and 246 females met the inclusion criteria for the study. Subjects with the following characteristics had higher odds (OR) of death: Older age [OR 8.3 (95% CI 1.1-63.1, p = 0.04)] for subjects age 70 or more compared to subjects age 18-29); Hypertension [OR 3.6 (95% CI 1.6-7.8, p = 0.001)]; Diabetes [OR 3.1 (95% CI 1.7-5.6, p<0.001)]; COPD [OR 3.4 (95% CI 1.8-6.3, p<0.001)] and CKD stage 2 or greater [OR 2.5 (95% CI 1.3-4.9, p = 0.006)]. Combining all age groups, subjects with hypertension had significantly greater odds of the following adverse outcomes: requiring hospital admission (OR 2.2, 95% CI 1.4-3.4, p<0.001); needing respiratory support in 24 hours (OR 2.5, 95% CI: 1.7-3.7, p<0.001); ICU admission (OR 2.7, 95% CI 1.7-4.4, p<0.001); and death (OR 3.6, 95% CI 1.6-7.8, p = 0.001). Hypertension was not associated with needing vent in 24 hours (p = 0.07).

conclusionAge and hypertension were associated with significant comorbidity and mortality in Covid-19 Positive patients. Furthermore, people who were older than 70, and had hypertension, diabetes, COPD, or CKD had higher odds of dying from the disease as compared to patients who hadn't. Subjects with hypertension also had significantly greater odds of other adverse outcomes.

Indexed as

AdolescentAdultAgedAge FactorsComorbidityCOVID-19Diabetes MellitusFemaleHospital MortalityHumansHypertensionIntensive Care UnitsMaleMiddle AgedOhioPulmonary Disease, Chronic Obstructive

Identifiers

PMID33886663
PMCPMC8061926
OpenAlexW3155003517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.