Evidence map›Paper›PMID 33886642›Full record

ArticlePloS one2021

Effects of distancing and pattern of breathing on the filtering capability of commercial and custom-made facial masks: An in-vitro study.

Lorenzo Ball, Stefano Alberti, Claudio Belfortini, Chiara Almondo, Chiara Robba, Denise Battaglini, Carlo Cravero, Paolo Pelosi, Valentina Caratto, Maurizio Ferretti

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lorenzo BallDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genova, Italy.ORCID 0000-0002-3876-4730
Stefano AlbertiDepartment of Chemistry and Industrial Chemistry, University of Genoa, Genova, Italy.ORCID 0000-0002-5890-3232
Claudio BelfortiniDepartment of Chemistry and Industrial Chemistry, University of Genoa, Genova, Italy.
Chiara AlmondoDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genova, Italy.
Chiara RobbaDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genova, Italy.
Denise BattagliniDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genova, Italy.
Carlo CraveroDepartment of Mechanical, Energetic, Management and Transports Engineering, University of Genoa, Genova, Italy.
Paolo PelosiDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genova, Italy.
Valentina CarattoDepartment of Chemistry and Industrial Chemistry, University of Genoa, Genova, Italy.
Maurizio FerrettiDepartment of Chemistry and Industrial Chemistry, University of Genoa, Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince the beginning of the COVID-19 pandemics, masking policies have been advocated. While masks are known to prevent transmission towards other individuals, it is unclear if different types of facial masks can protect the user from inhalation. The present study compares in-vitro different commercial and custom-made facial masks at different distances and breathing patterns.

methodsMasks were placed on a head mannequin connected to a lung simulator, using a collecting filter placed after the mannequin airway. Certified, commercial and custom-made masks were tested at three different distances between the emitter and the mannequin: 40 cm, 80 cm and 120 cm. Two patterns of breathing were used, simulating normal and polypneic respiration. A solution of methylene blue was nebulized with a jet nebulizer and different mask-distance-breathing pattern combinations were tested. The primary endpoint was the inhaled fraction, defined as the amount of methylene blue detected with spectrophotometry expressed as percent of the amount detected in a reference condition of zero distance and no mask.

findingsWe observed a significant effect of distance (p < 0.001), pattern of breathing (p = 0.040) and type of mask (p < 0.001) on inhaled fraction. All masks resulted in lower inhaled fraction compared to breathing without mask (p < 0.001 in all comparisons), ranging from 41.1% ± 0.3% obtained with a cotton mask at 40 cm distance with polypneic pattern to <1% for certified FFP3 and the combination of FFP2 + surgical mask at all distances and both breathing pattern conditions. DISCUSSION: Distance, type of device and breathing pattern resulted in highly variable inhaled fraction. While the use of all types of masks resulted relevantly less inhalation compared to distancing alone, only high-grade certified devices (FFP3 and the combination of FFP2 + surgical mask) ensured negligible inhaled fraction in all conditions.

Indexed as

MasksPhysical DistancingCOVID-19Equipment DesignHumansManikinsRespirationSARS-CoV-2

Identifiers

PMID33886642
PMCPMC8062003

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.