ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021
In vivo assessment of changes to canine airway smooth muscle following bronchial thermoplasty with OR-OCT.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- In vivo polarisation sensitive optical coherence tomography for fibrosis assessment in interstitial lung disease: a prospective, exploratory, observational study.BMJ open respiratory research · 2023Observational
- Polarization-Sensitive Endobronchial Optical Coherence Tomography for Microscopic Imaging of Fibrosis in Interstitial Lung Disease.American journal of respiratory and critical care medicine · 2022Article
- Polarization-sensitive optical coherence tomography in end-stage lung diseases: an ex vivo pilot study.Biomedical optics express · 2021Article
- Bronchial thermoplasty for severe asthma: potential mechanisms and response markers.Therapeutic advances in respiratory diseaseReview
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
The inability to assess and measure changes to the airway smooth muscle (ASM) in vivo is a major challenge to evaluating asthma and its clinical outcomes. Bronchial thermoplasty (BT) is a therapy for asthma that aims to reduce the severity of excessive bronchoconstriction by ablating ASM. Although multiple long-term clinical studies of BT have produced encouraging results, the outcomes of BT treatment in practice have been variable, and questions remain regarding the selection of patients. Previously, we have demonstrated an imaging platform called orientation-resolved optical coherence tomography that can assess ASM endoscopically using an imaging catheter compatible with bronchoscopy. In this work, we present results obtained from a longitudinal BT study performed using a canine model (
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