ArticleJournal of neuro-oncology2021
The growth rate and clinical outcomes of radiation induced meningioma undergoing treatment or active monitoring.
Article in Journal of neuro-oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Stereotactic radiosurgery for radiation‑induced meningiomas: long‑term institutional outcomes with patient- and lesion‑level analyses and an updated meta‑analysis.Journal of neuro-oncology · 2025Pooled it
- High-grade glioma with dural progression: A single-center case series and review of literature.Radiology case reports · 2026Article
- Late-onset vascular and tumor complications after childhood brain radiotherapy: A rare case of dual sequelae.Radiology case reports · 2026Article
- Human Meningiomas Reveal No Evidence of Neuroendocrine Differentiation.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026Article
- Radiation-Induced Sphenoid Wing Meningioma After Childhood Medulloblastoma: A Case Report.Cureus · 2026Article
- Radiation-induced meningiomas: A systematic review and meta-analysis of 927 meningiomas.Surgical neurology international · 2026Review
- Oral contraceptives with progestogens desogestrel or levonorgestrel and risk of intracranial meningioma: national case-control study.BMJ (Clinical research ed.) · 2025Article
- An Extracranial, Infratemporal Meningioma Following Neoadjuvant Radiotherapy: A Case Report.Cureus · 2025Article
- Radiation-Induced Meningiomas Have an Aggressive Clinical Course: Genetic Signature Is Limited toJournal of Korean medical science · 2025Article
- Chronic Neurological Complications of Brain Tumors and Brain Tumor Treatments.Current neurology and neuroscience reports · 2025Review
- Skull-meninges-brain connectivity and extra-axial brain tumours.Brain communications · 2025Review
- Malignant Transformation of Meningiomas.Journal of Cancer · 2025Review
- Review
- Stereotactic radiotherapy of radiation-induced meningioma previously irradiated retrobulbar for Graves' ophthalmopathy: A case report.Radiology case reports · 2024Article
- Case report: Low-dose radiation-induced meningioma with a short latency period.Frontiers in oncology · 2024Article
- Multiple meningiomas: Epidemiology, management, and outcomes.Neuro-oncology advances · 2023Article
- Outcomes of radiation-induced meningiomas treated with stereotactic radiosurgery.Journal of neuro-oncology · 2023Article
- Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement.European journal of endocrinology · 2022Review
- Article
Corrections and comments
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Authors and funding
16 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRadiation induced meningioma (RIM) incidence is increasing in line with improved childhood cancer survival. No optimal management strategy consensus exists. This study aimed to delineate meningioma growth rates from tumor discovery and correlate with clinical outcomes.
methodsRetrospective study of patients with a RIM, managed at a specialist tertiary neuroscience center (2007-2019). Tumor volume was measured from diagnosis and at subsequent interval scans. Meningioma growth rate was determined using a linear mixed-effects model. Clinical outcomes were correlated with growth rates accounting for imaging and clinical prognostic factors.
resultsFifty-four patients (110 meningiomas) were included. Median duration of follow-up was 74 months (interquartile range [IQR], 41-102 months). Mean radiation dose was 41 Gy (standard deviation [SD] = 14.9) with a latency period of 34.4 years (SD = 13.7). Median absolute growth rate was 0.62 cm
conclusionRIMs exhibit high absolute and relative growth rates after discovery. Surgery is recommended for symptomatic or rapidly growing meningiomas only. Recurrence risk after surgery is high.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.