Evidence map›Paper›PMID 33885532›Full record

ArticleNanoscale2021

Efficient in vivo wound healing using noble metal nanoclusters.

Kuo Li, Dan Li, Cheng-Hsuan Li, Pengfei Zhuang, Chunmei Dai, Xiangka Hu, Dahao Wang, Yuanye Liu, Xifan Mei, Vincent M Rotello

RetractedAbstract readRetracted Publication
In one paragraph

Article in Nanoscale, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Nanomaterials in Skin Regeneration and Rejuvenation.International journal of molecular sciences · 2021
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Kuo LiDepartment of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, 40 Songpo Road, Jinzhou, China 121001, China. meixifan@jzmu.edu.cn.
Dan Li
Cheng-Hsuan Li
Pengfei Zhuang
Chunmei Dai
Xiangka Hu
Dahao Wang
Yuanye Liu
Xifan Mei
Vincent M Rotello

Funding

Engineered Polymer Nanoemulsions for Treatment of Wound Biofilm InfectionsR01AI134770 · NIAID · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Robin Patel, VINCENT M. ROTELLO · 2018 to 2026
$3.5M
NIAID NIH HHS R01 AI134770
6 · The paper itself

Abstract

The wound healing process involves multiple steps including hemostasis, inflammation, proliferation, and tissue remodeling. Nanomaterials have been employed externally for healing wounds. However, their use as systemic therapeutics has not been extensively explored. We report the use of ultra-small noble metal nanoclusters (NCs) for the treatment of skin wounds. Both in vitro and in vivo studies indicate NCs have comprehensive therapeutic effects for wound healing, promoting cell proliferation and migration while decreasing inflammation.

Indexed as

NanostructuresWound HealingCell ProliferationSkin

Identifiers

PMID33885532
PMCPMC8084111

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.