Evidence map›Paper›PMID 33885228›Full record

ArticleTherapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy2021

Evaluation of the performance, operability, and safety of Plasauto μ, a new type of machine for cell-free and concentrated ascites reinfusion therapy, in a postmarketing clinical study.

Midori Hasegawa, Hiromichi Matsushita, Kensei Yahata, Akira Sugawara, Yoshitaka Ishibashi, Ryoko Kawahara, Yoshifumi Hamasaki, Hitoshi Kanno, Sachie Yamada, Norio Nii and 6 more

Abstract read
In one paragraph

Article in Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Evaluation of the performance, operability, and safety of Plasauto μ, a new type of machine for cell-free and concentrated ascites reinfusion therapy, in a postmarketing clinical study.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Midori HasegawaDepartment of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Hiromichi MatsushitaNational Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Kensei YahataJapanese Red Cross Osaka Hospital, Tennoji-ku, Osaka, Japan.
Akira SugawaraShizuoka General Hospital, Aoi-ku, Shizuoka, Japan.
Yoshitaka IshibashiJapanese Red Cross Medical Center, Shibuya-ku, Tokyo, Japan.
Ryoko KawaharaThe Cancer Institute Hospital of JFCR, Koto-ku, Tokyo, Japan.
Yoshifumi HamasakiThe University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Hitoshi KannoTokyo Women's Medical University Hospital, Shinjuku-ku, Tokyo, Japan.
Sachie YamadaCenter of Blood Purification, Fujita Health University Hospital, Toyoaka, Aichi, Japan.
Norio NiiCenter of Blood Purification, Fujita Health University Hospital, Toyoaka, Aichi, Japan.
Masao KatoCenter of Blood Purification, Fujita Health University Hospital, Toyoaka, Aichi, Japan.
Atsushi OhashiFaculty of Clinical Engineering, Fujita Health University School of Health Sciences, Toyoaka, Aichi, Japan.
Shigehisa KoideDepartment of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Hiroki HayashiDepartment of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Yukio YuzawaDepartment of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Naotake TsuboiDepartment of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.

Funding

Asahi Kasei Medical Co., Ltd
6 · The paper itself

Abstract

Cell-free and concentrated ascites reinfusion therapy (CART) is performed by collecting the ascites from the patient, followed by filtration and concentration. Thereafter, concentrated cell-free ascites is reinfused into the patient intravenously. The new type of machine, Plasauto μ, for managing the process of CART was launched onto the market. We have evaluated the machine through postmarketing clinical study in 17 patients with malignant ascites. The amounts of original and concentrated ascites were 3673 ± 1920 g and 439 ± 228 g, respectively. Recovery rates were acceptable regarding values of total protein, albumin, and IgG that were 55.6% ± 17.3%, 60.2% ± 20.8%, and 58.2% ± 20.5%, respectively. Recovery rates were positively associated with amounts of original ascites and negatively associated with total protein concentration. No adverse events related to the machine were observed. The new type of machine showed preferable performance in processing malignant ascites.

Indexed as

Cell-Free SystemProduct Surveillance, PostmarketingAdultAgedAged, 80 and overAscitesEquipment DesignFemaleFiltrationHumansMaleMiddle Ageda new type of machineascitescell-free and concentrated ascites reinfusion therapypost-marketing clinical studyrecovery rate

Identifiers

PMID33885228
PMCPMC8359940

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.