Evidence map›Paper›PMID 33885215›Full record

ArticleTherapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy2021

Novel adsorptive type apheresis device Immunopure for ulcerative colitis from clinical perspectives based on clinical trials: Japan and Europe.

Yoshihiro Endo, Motoki Yonekawa, Kazutaka Kukita, Masaki Katagiri, Takayuki Matsumoto, Keisuke Kawasaki, Shunichi Yanai, Shingo Kato, Kazuhito Kani, Tomonari Ogawa and 8 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Novel adsorptive type apheresis device Immunopure for ulcerative colitis from clinical perspectives based on clinical trials: Japan and Europe.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 1 country.

Yoshihiro EndoDepartment of Clinical Nursing, Shiga University of Medical Science, Otsu, Japan.
Motoki YonekawaDepartment of Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.
Kazutaka KukitaDepartment of Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.
Masaki KatagiriDepartment of Gastroenterology, Sapporo Hokuyu Hospital, Sapporo, Japan.
Takayuki MatsumotoDivision of Gastroenterology, Department of Medicine, Iwate Medical University, Yahaba, Japan.
Keisuke KawasakiDivision of Gastroenterology, Department of Medicine, Iwate Medical University, Yahaba, Japan.
Shunichi YanaiDivision of Gastroenterology, Department of Medicine, Iwate Medical University, Yahaba, Japan.
Shingo KatoDepartment of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Kazuhito KaniDepartment of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Tomonari OgawaDepartment of Nephrology and Hypertension, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Kazuya KitamuraDepartment of Gastroenterology, Kanazawa University Hospital, Kanazawa, Japan.
Izumi HasegawaDepartment of Gastroenterology and Hepatology, Japan Community Health Care Organization Chukyo Hospital, Nagoya, Japan.
Yusuke InoueDepartment of Gastroenterology and Hepatology, Japan Community Health Care Organization Chukyo Hospital, Nagoya, Japan.
Takuya DoiDepartment of Gastroenterology and Hepatology, Japan Community Health Care Organization Chukyo Hospital, Nagoya, Japan.
Kazuhide HiguchiSecond Department of Internal Medicine, Osaka Medical College, Takatsuki, Japan.
Ken KawakamiSecond Department of Internal Medicine, Osaka Medical College, Takatsuki, Japan.
Kazuki KakimotoSecond Department of Internal Medicine, Osaka Medical College, Takatsuki, Japan.
Hiroki NakamuraDivision of Gastroenterology and Hepatology, Shin-Koga Hospital, Kurume, Japan.
Chukyo Hospital · JPIwate Medical University · JPOsaka Medical and Pharmaceutical University · JPSapporo Hokuyu Hospital · JPSocial Insurance Saitama Chuo Hospital · JPKanazawa University Hospital · JPKoga Hospital · JPSaitama Medical University · JPShiga University of Medical Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several adsorptive type devices for ulcerative colitis are used for the induction of remission in patients with active severe disease worldwide. In 2020, the novel apheresis device Immunopure for ulcerative colitis was launched in Japan. Immunopure, like the polyethylene terephthalate column, uses polyarylate, a type of polyester resin, as the adsorbent. Similar to the cellulose acetate column, Immunopure is filled with adsorbent beads and expected to provide ease of use, with minimal risk of column clogging. Immunopure adsorbs leukocytes and platelets, especially activated platelets and platelet-leukocyte aggregates. In this article, the capability of Immunopure is evaluated from clinical perspective based on a clinical trial in Japan/Europe. As a result, Immunopure is comparable to other products in clinical effectiveness and indicated for the treatment of patients with refractory moderate ulcerative colitis, making it highly useful in clinical practice.

Indexed as

AdsorptionBlood Component RemovalCelluloseColitis, UlcerativeEquipment DesignEuropeFemaleHumansMalePolyestersPolyethylene TerephthalatesRemission InductionacetylcelluloseCellulosePolyestersPolyethylene Terephthalatesadsorptive deviceaggregationgranulocyteleukocytemoderatemonocytepolyarylate resintherapeutic apheresisulcerative colitis

Identifiers

PMID33885215
PMCPMC8359836
OpenAlexW3154312465

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.