Evidence map›Paper›PMID 33885205›Full record

ReviewThe oncologist2021

Pancreas Cancer-Associated Pain Management.

Andrew L Coveler, Jonathan Mizrahi, Bory Eastman, Smith Jim Apisarnthanarax, Shalini Dalal, Terry McNearney, Shubham Pant, Precision Promise Consortium

Open access · bronzeAbstract readReview
In one paragraph

Review in The oncologist, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 2 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Palliative care in pancreatic cancer: effects on symptom burden, survival, and place of death.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  12. Review
  13. Enhancing management of pancreatic cancer: impact of a same day multidisciplinary clinic on access to guideline-directed care.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2025
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Andrew L CovelerDepartment of Medical Oncology, University of Washington, Seattle, Washington, USA.ORCID 0000-0003-1710-5637
Jonathan MizrahiDepartment of Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Bory EastmanDepartment of Radiation Oncology, University of Washington, Seattle, Washington, USA.
Smith Jim ApisarnthanaraxDepartment of Radiation Oncology, University of Washington, Seattle, Washington, USA.
Shalini DalalDepartment of Palliative, Rehabilitation and Integrative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Terry McNearneyPancreatic Cancer Action Network, Galveston, Texas, USA.
Shubham PantDepartment of Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Precision Promise Consortium
The University of Texas MD Anderson Cancer Center · USUniversity of Washington · USPancreatic Cancer Action Network · USUniversity of Washington Medical Center · US

Funding

TRAINING FOR ACADEMIC ONCOLOGY/HEMATOLOGYT32CA009666 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Michael Davies, Courtney DiNardo · 1994 to 2026
$9.8M
NCI NIH HHS T32 CA009666
6 · The paper itself

Abstract

Pain is highly prevalent in patients with pancreas cancer and contributes to the morbidity of the disease. Pain may be due to pancreatic enzyme insufficiency, obstruction, and/or a direct mass effect on nerves in the celiac plexus. Proper supportive care to decrease pain is an important aspect of the overall management of these patients. There are limited data specific to the management of pain caused by pancreatic cancer. Here we review the literature and offer recommendations regarding multiple modalities available to treat pain in these patients. The dissemination and adoption of these best supportive care practices can improve quantity and quality of life for patients with pancreatic cancer. IMPLICATIONS FOR PRACTICE: Pain management is important to improve the quality of life and survival of a patient with cancer. The pathophysiology of pain in pancreas cancer is complex and multifactorial. Despite tumor response to chemotherapy, a sizeable percentage of patients are at risk for ongoing cancer-related pain and its comorbid consequences. Accordingly, the management of pain in patients with pancreas cancer can be challenging and often requires a multifaceted approach.

Indexed as

Cancer PainCeliac PlexusPancreatic NeoplasmsHumansPain ManagementPalliative CarePancreasQuality of LifePain managementPalliative carePancreatic neoplasms

Identifiers

PMID33885205
PMCPMC8176967
OpenAlexW3153308376

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.