Evidence map›Paper›PMID 33884911›Full record

ArticleThe Journal of international medical research2021

Clinical and reproductive outcomes of uterine smooth muscle tumor of uncertain malignant potential: a single-center retrospective study.

Chengcheng Ning, Lihong Zhang, Chenyan Zhao, Xiaojun Chen, Xiaoxia Liu, Chao Gu

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PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chengcheng NingDepartment of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Lihong ZhangDepartment of Pathology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Chenyan ZhaoDepartment of Pathology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Xiaojun ChenDepartment of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Xiaoxia LiuDepartment of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Chao GuDepartment of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-6045-9532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical outcomes, histopathological features, and obstetric and oncological outcomes of uterine smooth muscle tumor of uncertain malignant potential (STUMP).

methodsWe conducted a single-center, database review of patients with STUMP between January 2001 and December 2015. We investigated the clinical, operative, histopathologic, recurrence, and fertility outcomes of the included cases.

resultsNineteen patients with STUMP were studied. Three were reclassified as sarcoma after slide review, and 16 patients were finally included in the study. The mean age was 45 years. Ki-67 expression was ≥10% in 25.0% of cases and 30% in the only recurrent case. Recurrence occurred 52 months after a diagnosis of STUMP in a 56-year-old female patient who underwent hysterectomy. Two of six patients who underwent myomectomy had fertility requirements, and both successfully delivered babies without recurrence. Recurrence was not related to mitosis, degree of atypia, or necrosis. There was also no relationship between type of surgery or surgical approach and recurrence.

conclusionsPatients with STUMP warrant a pathological review process in centers with experience. Fertility-preservation is worth attempting, but young patients must be followed-up closely. Ki-67 might be a valuable marker predicting recurrence.

Indexed as

Smooth Muscle TumorUterine MyomectomyUterine NeoplasmsFemaleHumansMiddle AgedNeoplasm Recurrence, LocalPregnancyRetrospective Studiesfertility preservationKi-67leiomyosarcomamyomectomyrecurrenceUterine smooth muscle tumor of uncertain malignant potential

Identifiers

PMID33884911
PMCPMC8074534

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.