Evidence map›Paper›PMID 33884542›Full record

ArticleEuropean journal of epidemiology2021

Nationwide seroprevalence of antibodies against SARS-CoV-2 in Israel.

Shay Reicher, Ronit Ratzon, Shay Ben-Sahar, Sharon Hermoni-Alon, David Mossinson, Yotam Shenhar, Michael Friger, Yaniv Lustig, Sharon Alroy-Preis, Emilia Anis and 2 more

Abstract read
In one paragraph

Article in European journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  5. Article
  6. Observational
  7. Article
  8. Article
  9. Long-Term Antibody Response to SARS-CoV-2 in Children.Journal of clinical immunology · 2023
    Article
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  13. Review
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  17. A global assessment of the impact of school closure in reducing COVID-19 spread.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shay ReicherPublic Health Services, Ministry of Health, 39 Yirmiyahu Street, Jerusalem, Israel. shay.reicher@moh.gov.il.ORCID http://orcid.org/0000-0002-0858-4317
Ronit RatzonPublic Health Services, Ministry of Health, 39 Yirmiyahu Street, Jerusalem, Israel.
Shay Ben-SaharSchneider Children's Medical Center, Clalit Research Institute, Petach Tikva, Israel.
Sharon Hermoni-AlonMaccabi Healthcare Group, 27 Hamered, Tel Aviv, Israel.
David MossinsonMeuhedet Health Services, 124 Ibn Gvirol Street, Tel Aviv, Israel.
Yotam ShenharLeumit Health Services, 3 Ariel Sharon Street, Or Yehuda, Israel.
Michael FrigerFaculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
Yaniv LustigCentral Virology Laboratory, Ministry of Health and Sheba Medical Center, Tel-Hashomer, Israel.
Sharon Alroy-PreisPublic Health Services, Ministry of Health, 39 Yirmiyahu Street, Jerusalem, Israel.
Emilia AnisPublic Health Services, Ministry of Health, 39 Yirmiyahu Street, Jerusalem, Israel.
Siegal SadetzkiSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ehud KalinerPublic Health Services, Ministry of Health, 39 Yirmiyahu Street, Jerusalem, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The first local spread of COVID-19 in Israel was detected in March 2020. Due to the diversity in clinical presentations of COVID-19, diagnosis by RT-PCR alone might miss patients with mild or no symptoms. Serology testing may better evaluate the actual magnitude of the spread of infection in the population. This is the first nationwide seroprevalence study conducted in Israel. It is one of the most widespread to be conducted thus far, and the largest per-country population size. The survey was conducted between June 28 and September 14, 2020 and included 54,357 patients who arrived at the Health Maintenance Organizations to undergo a blood test for any reason. A patient was considered seropositive after two consecutive positive results with two different kits (Abbott and DiaSorin).The overall seroprevalence was 3.8% (95%CI 3.7-4.0), males higher than females [4.9% (95%CI 4.6-5.2) vs. 3.1% (95%CI 2.9-3.3) respectively]. Adolescents had the highest prevalence [7.8% (95%CI 7.0-8.6)] compared to other age groups. Participants who had undergone RT-PCR testing had a tenfold higher risk to be seropositive. The prevalence-to-incidence ratio was 4.5-15.7. Serology testing is an important complimentary tool for assessing the actual magnitude of infection and thus essential for implementing policy measures to control the pandemic. A positive serology test result was recently accepted in Israel as being sufficient to define recovery, with possible far-reaching consequences, such as the deploying of employees to ensure the maintenance of a functional economy.

Indexed as

COVID-19 Serological TestingAdolescentAdultAgedAged, 80 and overAntibodies, ViralBiomarkersChildChild, PreschoolCOVID-19COVID-19 Nucleic Acid TestingFemaleHumansIncidenceInfantInfant, NewbornAntibodies, ViralBiomarkersCOVID-19EpidemiologySARS-CoV-2SerologySeroprevalence

Identifiers

PMID33884542
PMCPMC8059683

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.