Evidence map›Paper›PMID 33884539›Full record

ArticleAnnals of biomedical engineering2021

Novel Composite Gold-Aluminum Electrode with Application to Neural Recording and Stimulation in Ultrahigh Field Magnetic Resonance Imaging Scanners.

Corey E Cruttenden, Mahdi Ahmadi, Yi Zhang, Xiao-Hong Zhu, Wei Chen, Rajesh Rajamani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Corey E CruttendenDepartment of Mechanical Engineering, University of Minnesota, Minneapolis, MN, USA.
Mahdi AhmadiDepartment of Mechanical Engineering, University of Minnesota, Minneapolis, MN, USA.
Yi ZhangCenter for Magnetic Resonance Research (CMRR), Radiology Department, University of Minnesota, Minneapolis, MN, USA.
Xiao-Hong ZhuCenter for Magnetic Resonance Research (CMRR), Radiology Department, University of Minnesota, Minneapolis, MN, USA.
Wei ChenCenter for Magnetic Resonance Research (CMRR), Radiology Department, University of Minnesota, Minneapolis, MN, USA.
Rajesh RajamaniDepartment of Mechanical Engineering, University of Minnesota, Minneapolis, MN, USA. rajamani@umn.edu.ORCID http://orcid.org/0000-0001-9931-7419

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger, KAMIL UGURBIL · 2019 to 2026
$11.7M
Integrated fMRI Methods to Study Neurophysiology and Circuit Dynamics at Laminar and Columnar LevelR01MH111413 · NIMH · UNIVERSITY OF MINNESOTA · PI CHEN, WEI · 2016 to 2020
$4.4M
Institutional Center Cores for Advanced NeuroimagingP30NS076408 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2020
$4.2M
Ultra High Field (16.4 Tesla) Animal MRI/MRS SystemS10RR025031 · NCRR · UNIVERSITY OF MINNESOTA · PI GARWOOD, MICHAEL · 2008 to 2008
$2.0M
NCRR NIH HHS S10 RR025031NIBIB NIH HHS P41 EB027061NIH HHS P30 NS076408NIH HHS P41 EB027061NIH HHS R01 MH111413NIH HHS S10 RR025031NIMH NIH HHS R01 MH111413NINDS NIH HHS P30 NS076408
6 · The paper itself

Abstract

Traditional electrodes used for neural recording and stimulation generate large regions of signal void (no functional MRI signal) when used in ultrahigh field (UHF) MRI scanners. This is a significant disadvantage when simultaneous neural recording/stimulation and fMRI signal acquisition is desired, for example in understanding the functional mechanisms of deep brain stimulation (DBS). In this work, a novel gold-aluminum microwire neural electrode is presented which overcomes this disadvantage. The gold-aluminum design greatly reduces the magnetic susceptibility difference between the electrode and brain tissue leading to significantly reduced regions of signal void. Gold-aluminum microwire samples are imaged at ultrahigh field 16.4 Tesla and compared with gold-only and aluminum-only microwire samples. First, B

Indexed as

AluminumGoldAnimalsBrainElectrodesEquipment DesignMagnetic Resonance ImagingPhantoms, ImagingRatsRats, Sprague-DawleyAluminumGoldGold-aluminum electrodesImage artifactsMatched magnetic susceptibilityMRI scannersNeural electrodes

Identifiers

PMID33884539
PMCPMC8458236

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.