Evidence map›Paper›PMID 33884510›Full record

ArticleAIDS and behavior2021

A Behavioral Cascade of HIV Seroadaptation Among US Men Who Have Sex with Men in the Era of PrEP and U = U.

Steven M Goodreau, Kevin M Maloney, Travis H Sanchez, Martina Morris, Patrick Janulis, Samuel M Jenness

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  7. Navigating the Viral Divide: Sexual and Gender Minority Community Perspectives on Treatment as Prevention.AIDS education and prevention : official publication of the International Society for AIDS Education · 2023
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Steven M GoodreauDepartment of Anthropology and Center for Studies in Demography and Ecology, University of Washington, Campus Box 353100, Seattle, WA, 91895, USA. goodreau@uw.edu.ORCID http://orcid.org/0000-0003-1009-5763
Kevin M MaloneyDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Travis H SanchezDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Martina MorrisDepartments of Statistics and Sociology, University of Washington, Seattle, WA, USA.
Patrick JanulisDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Samuel M JennessDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Emory University · USUniversity of Washington · USNorthwestern University · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI CONNIE L CELUM · 1988 to 2026
$104.9M
Methods and Data CoreR24HD042828 · NICHD · UNIVERSITY OF WASHINGTON · PI TOLNAY, STEWART E · 2002 to 2016
$9.3M
Scientific/Technical CoreP2CHD042828 · NICHD · UNIVERSITY OF WASHINGTON · PI SARA R. CURRAN · 2017 to 2026
$6.3M
EpiModel 2.0: Integrated Network Models for HIV/STI Prevention ScienceR01AI138783 · NIAID · EMORY UNIVERSITY · PI JENNESS, SAMUEL · 2018 to 2021
$3.0M
Modeling Antiretroviral-Based Prevention among MSM in the USR21MH112449 · NIMH · EMORY UNIVERSITY · PI JENNESS, SAMUEL · 2017 to 2018
$442k
National Institute of Allergy and Infectious Diseases AI138783NIAID NIH HHS P30 AI027757NIAID NIH HHS R01 AI138783NICHD NIH HHS P2C HD042828NICHD NIH HHS R24 HD042828NIMH NIH HHS R21 MH112449
6 · The paper itself

Abstract

Seroadaptive behaviors help reduce HIV risk for some men who have sex with men (MSM), and have been well documented across MSM populations. Advancements in biomedical prevention have changed the contexts in which seroadaptive behaviors occur. We thus sought to estimate and compare the prevalence of four stages of the "seroadaptive cascade" by PrEP use in the recent era: knowledge of own serostatus, knowledge of partner serostatus; serosorting (matching by status), and condomless anal intercourse. Serosorting overall appeared to remain common, especially with casual and one-time partners. Although PrEP use did not impact status discussion, it did impact serosorting and the likelihood of having condomless anal intercourse. For respondents not diagnosed with HIV and not on PrEP, condomless anal intercourse occurred in just over half of relationships with HIV-positive partners who were not on treatment. Biomedical prevention has intertwined with rather than supplanted seroadaptive behaviors, while contexts involving neither persist.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesCondomsHIV SerosortingHomosexuality, MaleHumansMaleSexual BehaviorSexual PartnersCondom useHIV-1Men who have sex with menPre-exposure prophylaxis (PrEP)Seroadaptive behaviorsTreatment as prevention (TasP)

Identifiers

PMID33884510
PMCPMC8528882
OpenAlexW3109127628

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.