ArticleCerebral cortex (New York, N.Y. : 1991)2021
Left-Handers Are Less Lateralized Than Right-Handers for Both Left and Right Hemispheric Functions.
Article in Cerebral cortex (New York, N.Y. : 1991), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cerebral lateral ventricular asymmetry: a meta-analysis and meta-regression of volumetric MRI studies.Neuroradiology · 2026Pooled it
- A comprehensive scoping review and meta-analysis of upper limb strength asymmetry.Scientific reports · 2025Pooled it
- Change in brain asymmetry reflects level of acute alcohol intoxication and impacts on inhibitory control.Scientific reports · 2023Trial
- Reduced prefrontal total choline MRS levels characterize the neurodevelopmental phenotype of bipolar disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Pallidal and subthalamic stimulations modulate inter-hemispheric interaction and asymmetry in Parkinson's disease.Molecular psychiatry · 2026Article
- The impact of hand dominance on haptic and visual size comparisons.Psychological research · 2026Article
- Mean Apparent Propagator MRI: A Potential Imaging Biomarker of Brain Microstructural Alterations in Basic-Type Intermittent Exotropia.Investigative ophthalmology & visual science · 2026Article
- Rapid modulation of choice behavior by ultrasound on the human frontal eye fields.Nature communications · 2026Article
- Organization of affordance processing in perception-action systems.Frontiers in human neuroscience · 2026Article
- The Effects of Handedness Consistency on the Identification of Own- and Cross-Race Faces.Brain sciences · 2025Article
- Effect of electroacupuncture on anxiety in patients with obesity: a protocol for a randomised, blinded, sham-controlled trial.BMJ open · 2025Article
- Cerebral Lateralization During Handwritten and Typed Word Generation: A Functional Transcranial Doppler Ultrasound Study in Left-Handers and Right-Handers.The European journal of neuroscience · 2025Observational
- Effects of Lateralization of Language on Cognition Among Left-Handers.Neurobiology of language (Cambridge, Mass.) · 2025Article
- The reliability of bilateral cerebral laterality for word generation: Who is left in the middle?Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Advanced brain aging mediates the relationship between cardiovascular health and aphasia severity in chronic stroke.Aging brain · 2025Article
- Revisiting atypical language lateralization in dyslexia.Brain communications · 2025Article
- Lateral asymmetry of emotional arousal as a biomarker of attributional style during darts competitions.Biologia futura · 2024Article
- Evaluating the gonads of left-handed children using ultrasonography and comparing the findings with those of right-handed ones.European journal of pediatrics · 2024Article
- Atypical lateralization of visuospatial attention can be associated with better or worse performance on line bisection.Brain structure & function · 2024Article
- Lateralization of major white matter tracts during infancy is time-varying and tract-specific.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
Corrections and comments
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3 authors.
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Abstract
Many neuroscientific techniques have revealed that more left- than right-handers will have unusual cerebral asymmetries for language. After the original emphasis on frequency in the aphasia and epilepsy literatures, most neuropsychology, and neuroimaging efforts rely on estimates of central tendency to compare these two handedness groups on any given measure of asymmetry. The inevitable reduction in mean lateralization in the left-handed group is often postulated as being due to reversed asymmetry in a small subset of them, but it could also be due to a reduced asymmetry in many of the left-handers. These two possibilities have hugely different theoretical interpretations. Using functional magnetic resonance imaging localizer paradigms, we matched left- and right-handers for hemispheric dominance across four functions (verbal fluency, face perception, body perception, and scene perception). We then compared the degree of dominance between the two handedness groups for each of these four measures, conducting t-tests on the mean laterality indices. The results demonstrate that left-handers with typical cerebral asymmetries are less lateralized for language, faces, and bodies than their right-handed counterparts. These results are difficult to reconcile with current theories of language asymmetry or of handedness.
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Registered trials
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