Evidence map›Paper›PMID 33884279›Full record

ArticleOpen forum infectious diseases2021

Pyomyositis and Infectious Myositis: A Comprehensive, Single-Center Retrospective Study.

Christopher Radcliffe, Savanah Gisriel, Yu Si Niu, David Peaper, Santiago Delgado, Matthew Grant

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  4. Article
  5. Antimicrobial resistance and virulence gene patterns ofEuropean journal of translational myology · 2026
    Article
  6. Article
  7. Diffuse Unilateral Leg Swelling.Journal of the American College of Emergency Physicians open · 2025
    Review
  8. A Case Report of Inferior Rectus Abscess.Journal of education & teaching in emergency medicine · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Primary MRSA Myositis Mimicking Septic Arthritis.Case reports in critical care · 2023
    Article
  20. Streptococcal pyomyositis in asplenia and underlying connective tissue disease.Proceedings (Baylor University. Medical Center) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christopher RadcliffeYale University School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0001-8352-1482
Savanah GisrielDepartment of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA.
Yu Si NiuYale University School of Medicine, New Haven, Connecticut, USA.
David PeaperYale University School of Medicine, New Haven, Connecticut, USA.
Santiago DelgadoDepartment of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA.
Matthew GrantYale University School of Medicine, New Haven, Connecticut, USA.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

backgroundPyomyositis is a bacterial infection of skeletal muscle that classically leads to abscess formation. A related, but distinct, entity is infectious myositis. The epidemiology of these infections has changed in recent years.

methodsTo better characterize both pyomyositis and infectious myositis, we conducted a retrospective study at our tertiary care institution. We identified 43 cases of pyomyositis and 18 cases of infectious myositis treated between January 2012 and May 2020.

resultsThe mean age of patients was 48 years, and 66% were male. Diabetes mellitus affected one third of patients, and 16% had other immunocompromising comorbidities. Staphylococcal species accounted for 46% of all infections, and common symptoms included muscle pain (95%) and subjective fever (49%). Altered mental status was a presenting symptom in 16% of cases. Approximately half of all patients received >1 class of antibiotic, and the median length of antimicrobial therapy was 18 days. Open and percutaneous drainage procedures figured prominently in the management of these infections, with 28% of patients requiring multiple procedures. Pathology specimens were available for 12 of 61 cases. Overall, the treatment success rate was 84%.

conclusionsGram-positive bacteria accounted for most infections at our institution, and management commonly involved open or percutaneous drainage procedures. Future studies that prospectively evaluate treatment strategies for pyomyositis and infectious myositis are warranted.

Indexed as

infectious myositismusclepyomyositisStaphylococcus aureus

Identifiers

PMID33884279
PMCPMC8047863
OpenAlexW3134989470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.