ArticleJournal of pediatric intensive care2021
Sequential Organ Failure Assessment Score As a Predictor of Outcome in Sepsis in Pediatric Intensive Care Unit.
Article in Journal of pediatric intensive care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Prognostic accuracy of SOFA and qSOFA for mortality among children with infection: a meta-analysis.Pediatric research · 2023Pooled it
- Development of Cereblon (CRBN) as an early prognostic biomarker in Paediatric Sepsis: a Prospective Observational Study Protocol.BMJ open · 2026Observational
- Diagnostic and Prognostic Value of Ferritin and Soluble Interleukin-2 Receptor α in Critically Ill Children with Hyperferritinemia.Diagnostics (Basel, Switzerland) · 2026Article
- Prognostic Accuracy of Serially Measured Organ Dysfunction Scores in Children with Fluid Refractory Septic Shock.Indian pediatrics · 2026Article
- Clinical profile, intensive care needs, outcome, and predictors of mortality in children with severe sepsis: Secondary analysis of FerriPedS study.The Indian journal of medical research · 2026Article
- [Prognostic value of critical illness scores and the ratio of neutrophil count to lymphocyte and platelet count for predicting 28-day mortality in pediatric sepsis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Article
- Utility of Phoenix Sepsis Score for Predicting Mortality in Pediatric Sepsis: A Prospective Analytical Study from a Resource-limited Pediatric Intensive Care Unit in Eastern India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- pSOFA score serves as predicting the severity and outcome of sepsis in critically ill children.Scientific reports · 2025Article
- Serum amyloid A and proadrenomedullin as early markers in critically ill children with sepsis.Clinical and experimental pediatrics · 2025Article
- Article
- Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world.The Lancet. Digital health · 2024Review
- Predictive value of laboratory indicators for in-hospital death in children with community-onset sepsis: a prospective observational study of 266 patients.BMJ paediatrics open · 2024Observational
- Review
- Predicting functional and quality-of-life outcomes following pediatric sepsis: performance of PRISM-III and PELOD-2.Pediatric research · 2023Article
- Children are small adults (when properly normalized): Transferrable/generalizable sepsis prediction.Surgery open science · 2023Article
- Serial Evaluation of Sequential Organ Failure Assessment Score (SOFA) as a Predictor of Outcome in Children Admitted in Pediatric Intensive Care Unit (PICU) at Tertiary Care Hospital.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023Article
- Predicting Pediatric ICU Outcomes: Yet Another SOFA (Study) on the PODIUM?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023Article
- The Various Scoring Systems in Pediatric Intensive Care Units: A Prospective Observational Study.Cureus · 2023Article
- Predictability of Pediatric Sepsis Outcome Using SEPSIS-3 Definition in a Single Tertiary Pediatric Institution.Translational perioperative and pain medicine · 2023Article
- Incidence of Hemodynamic Changes Following Intravenous Acetaminophen Administration in Critically Ill Pediatric Patients.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sequential organ failure assessment (SOFA) score is used as a predictor of outcome of sepsis in the pediatric intensive care unit. The aim of the study is to determine the application of SOFA scores as a predictor of outcome in children admitted to the pediatric intensive care unit with a diagnosis of sepsis. The design involved is prospective observational study. The study took place at the multidisciplinary pediatric intensive care unit (PICU), tertiary care hospital, South India. The patients included are children, aged 1 month to 18 years admitted with a diagnosis of sepsis (suspected/proven) to a single center PICU in India from November 2017 to November 2019. Data collected included the demographic, clinical, laboratory, and outcome-related variables. Severity of illness scores was calculated to include SOFA score day 1 (SF1) and day 3 (SF3) using a pediatric version (pediatric SOFA score or pSOFA) with age-adjusted cutoff variables for organ dysfunction, pediatric risk of mortality III (PRISM III; within 24 hours of admission), and pediatric logistic organ dysfunction-2 or PELOD-2 (days 1, 3, and 5). A total of 240 patients were admitted to the PICU with septic shock during the study period. The overall mortality rate was 42 of 240 patients (17.5%). The majority (59%) required mechanical ventilation, while only 19% required renal replacement therapy. The PRISM III, PELOD-2, and pSOFA scores correlated well with mortality. All three severity of illness scores were higher among nonsurvivors as compared with survivors (
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