ArticleJournal of rehabilitation medicine. Clinical communications2020
Rehabilitation of Patients with Platypnea-Orthodeoxia Syndrome in COVID-19 Pneumonia: Two Case Reports.
Article in Journal of rehabilitation medicine. Clinical communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 15 citations in OpenAlex.
- Characteristics and outcomes of reversible platypnoea-orthodeoxia syndrome in COVID-19 pneumonia.Singapore medical journal · 2026Observational
- A Case of Platypnea-Orthodeoxia Syndrome Following COVID-19 Pneumonia Treated in a Convalescent Rehabilitation Ward.Japanese journal of comprehensive rehabilitation science · 2026Article
- Transpulmonary bubble transit in patients hospitalised with COVID-19 pneumonia.BMJ open respiratory research · 2025Article
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- Article
- Oxygen Therapy During Activities of Daily Living Rehabilitation and Outcome in Patients With Severe-to-critical COVID-19.Archives of rehabilitation research and clinical translation · 2023Article
- Platypnea-Orthodeoxia Syndrome in Coronavirus Disease 2019 Pneumonia: A Case Report and Literature Review.International medical case reports journal · 2023Article
- Platypnea-orthodeoxia syndrome in SARS-CoV-2 related ARDS: a case report.Acta bio-medica : Atenei Parmensis · 2022Article
- Platypnea-Orthodeoxia Syndrome after SARS-CoV-2 interstitial pneumonia: an overview and an update on our patient.Acta bio-medica : Atenei Parmensis · 2022Review
- Severe Pneumonia Caused by SARS-CoV-2: A Novel Cause of Platypnoea-Orthodeoxia Syndrome.European journal of case reports in internal medicine · 2022Article
- Platypnea Orthodeoxia Due to a Patent Foramen Ovale and Intrapulmonary Shunting After Severe COVID-19 Pneumonia.The American journal of case reports · 2021Article
- Platypnoea-Orthodeoxia Syndrome in COVID-19.European journal of case reports in internal medicine · 2021Article
- Platypnea-Orthodeoxia and Patent Foramen Ovale in a Patient in the Setting of COVID-19.Texas Heart Institute journalArticle
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4 authors at 1 institution in 1 country.
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Abstract
Platypnea-orthodeoxia syndrome, characterized by dyspnoea and arterial desaturation while upright, is a rare complication of acute respiratory distress syndrome. We report here 2 patients with COVID-19 pneumonia, who were diagnosed with platypnea-orthodeoxia syndrome during commencement of rehabilitation, 18 and 9 days respectively after admission to the intensive care unit. Both patients presented with normocapnic hypoxaemia. One patient required mechanical ventilation with supplemental oxygen during intensive care, while the other required high-flow nasal oxygen therapy. The manifestations of platypnea-orthodeoxia syndrome were most prominent during physiotherapy, when verticalization was attempted, and hindered further mobilization out of bed, including ambulation. This report describes the clinical manifestations of platypnea-orthodeoxia syndrome and the rehabilitative strategies carried out for these 2 patients. The platypnea-orthodeoxia syndrome in these patients resolved after 65 and 22 days respectively from the day of detection. This report highlights this potentially under-recognized phenomenon, which may be unmasked during rehabilitation of patients with COVID-19 pneumonia. Good functional outcomes were achieved with a combination of verticalization training with supplemental oxygen support, respiratory techniques training and progressive endurance and resistance training, whilst awaiting resolution of the platypneaorthodeoxia syndrome.
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