Evidence map›Paper›PMID 33884011›Full record

ArticleIranian journal of parasitology

Fe3O4@Bio-MOF Nanoparticles Combined with Artemisinin, Glucantime®, or Shark Cartilage Extract on Iranian Strain of

Fatemeh Ghafarifar, Soheila Molaie, Reza Abazari, Zoheir-Mohammad Hasan, Masoud Foroutan

Open access · goldAbstract read
In one paragraph

Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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  8. In vitro Evaluation of the Potent Antileishmanial Activity ofIranian journal of pharmaceutical research : IJPR
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fatemeh GhafarifarDepartment of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Soheila MolaieArthropod Born Diseases Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.
Reza AbazariDepartment of Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Zoheir-Mohammad HasanDepartment of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Masoud ForoutanFaculty of Medical Sciences, Abadan University of Medical Sciences, Abadan, Iran.
Tarbiat Modares University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the present study, we examined the effects of Fe3O4@bio-MOF nanoparticle (Nano-FO) plus artemisinin (Art) and glucantime (Glu) or shark cartilage extract (ShCE) on

methodsThis experimental study was conducted at the laboratory of Department of Parasitology, Tarbiat Modares University, Tehran, Iran during 2016-2017. The promastigote and amastigote assays were performed were conducted at the presence of 3.12-400 μg/mL of the drug combinations. According to in vitro IC50 results, the combinations of 12.5μg/mL Nano-FO with 25 μg/mL Art as well as 200 μg/mL Glu and 0.5 mL of 20 mg/kg of ShCE were used to treat BALB/c mice. During and at the end of the treatment, the lesion sizes were measured. Parasite loads, cytokine levels were evaluated at the end of the treatment.

resultsThe IC

conclusionThis study suggested that Nano-FO/Art combination can be considered as an anti-leishmania combination therapy in CL induced by

Indexed as

ArtemisininGlucantimeLeishmania majorShark cartilage extract

Identifiers

PMID33884011
PMCPMC8039492
OpenAlexW3113021577

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.