ArticleEthiopian journal of health sciences2020
Comparison of Microscopy and PCR for Detection of
Article in Ethiopian journal of health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A 'One Health' perspective of Africa-wide distribution and prevalence of Giardia species in humans, animals and waterbodies: a systematic review and meta-analysis.Parasitology · 2023Pooled it
- Prevalence and molecular characterisation ofInternational journal for parasitology. Parasites and wildlife · 2026Article
- Intestinal parasitic infections and risk factors among schoolchildren in Taiz City Yemen.Scientific reports · 2026Article
- Prevalence ofJournal of veterinary research · 2025Article
- Assessment of Human Taeniasis and Other Intestinal Parasites in Narok County, Kenya.Veterinary medicine international · 2025Article
- Molecular characterization of Giardia duodenalis, Cryptosporidium spp., and Entamoeba spp. infecting domestic and feral/stray cats in Jordan.Parasitology research · 2024Article
- Routine ante-natal screening using maternal risk factors and biomarkers for preeclampsia in 11-13Journal of family medicine and primary care · 2024Article
- Genotyping and epidemiological distribution of diarrhea-causing isolates of Giardia duodenalis in southeastern part of West Bengal, India.Parasitology research · 2023Article
- Burden and Epidemiology of Human IntestinalTropical medicine and infectious disease · 2022Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccurate diagnosis of Giardia lamblia and Entamoeba histolytica is important since these intestinal parasites account for a significant proportion of morbidity and mortality globally. Microscopy is the key diagnostic test used for diagnosis of the two parasites. Other tests including rapid diagnostic tests and polymerase chain reaction have been developed to improve the detection of these parasites. Most of these newer tests are not affordable in resource limited settings, hence the over reliance on microscopy. The objective of this study was to determine the reliability of microscopy in a resource limited setting in Western Kenya, a region endemic for the two intestinal parasites.
methodsPolymerase chain reaction, the gold standard test, was performed on stool samples suspected for G. lamblia and E. histolytica. Microscopy was then performed on the same samples and the two tests compared.
resultsMicroscopy was found to be 64.4% sensitive, 86.6% specific for the detection of G. lamblia. Additionally, this test was 64.2% sensitive and 83.6% specific for the diagnosis of E. histolytica. Cohen's kappa values of 0.51 and 0.47 were determined for microscopy for G. lamblia and E. histolytica respectively. McNemar's test revealed a significant difference between the two tests, P<0.001.
conclusionThis study found microscopy to be a reliable diagnostic test in this resource limited setting.
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