Evidence map›Paper›PMID 33883784›Full record

ReviewAquaculture (Amsterdam, Netherlands)2021

Antiviral peptides from aquatic organisms: Functionality and potential inhibitory effect on SARS-CoV-2.

Tofael Ahmed Sumon, Md Ashraf Hussain, Mahmudul Hasan, Aminur Rashid, Muyassar Hamid Abualreesh, Won Je Jang, S M Sharifuzzaman, Christopher Lyon Brown, Eun-Woo Lee, Md Tawheed Hasan

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Aquaculture (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Antiviral Effect of MicroalgaeMarine drugs · 2024
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Tofael Ahmed SumonDepartment of Fish Health Management, Sylhet Agricultural University, Sylhet 3100, Bangladesh.
Md Ashraf HussainDepartment of Fisheries Technology and Quality Control, Sylhet Agricultural University, Sylhet 3100, Bangladesh.
Mahmudul HasanDepartment of Pharmaceuticals and Industrial Biotechnology, Sylhet Agricultural University, Sylhet 3100, Bangladesh.
Aminur RashidDepartment of Aquaculture, Sylhet Agricultural University, Sylhet 3100, Bangladesh.
Muyassar Hamid AbualreeshDepartment of Marine Biology, Faculty of Marine Science, King Abdulaziz University, P.O. Box 80207, Jeddah 21589, Saudi Arabia.
Won Je JangBiopharmaceutical Engineering Major, Division of Applied Bioengineering, Dong-Eui University, Busan 47340, Republic of Korea.
S M SharifuzzamanInstitute of Marine Sciences, University of Chittagong, Chittagong 4331, Bangladesh.
Christopher Lyon BrownFAO World Fisheries University Pilot Programme, Pukyong National University, Busan, South Korea.
Eun-Woo LeeBiopharmaceutical Engineering Major, Division of Applied Bioengineering, Dong-Eui University, Busan 47340, Republic of Korea.
Md Tawheed HasanDepartment of Aquaculture, Sylhet Agricultural University, Sylhet 3100, Bangladesh.
Sylhet Agricultural University · BDDong-Eui University · KRKing Abdulaziz University · SAPukyong National University · KRUniversity of Chittagong · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several antiviral peptides (AVPs) from aquatic organisms have been effective in interfering with the actions of infectious viruses, such as Human Immunodeficiency Virus-1 and Herpes Simplex Virus-1 and 2. AVPs are able to block viral attachment or entry into host cells, inhibit internal fusion or replication events by suppressing viral gene transcription, and prevent viral infections by modulating host immunity. Therefore, as promising therapeutics, the potential of aquatic AVPs for use against the COVID-19 pandemic caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is considered. At present no therapeutic drugs are yet available. A total of 32 AVPs derived from fish and shellfish species are discussed in this review paper with notes on their properties and mechanisms of action in the inhibition of viral diseases both in humans and animals, emphasizing on SARS-CoV-2. The molecular structure of novel SARS-CoV-2 with its entry mechanisms, clinical signs and symptoms are also discussed. In spite of only a few study of these AVPs against SARS-CoV-2, aquatic AVPs properties and infection pathways (entry, replication and particle release) into coronaviruses are linked in this paper to postulate an analysis of their potential but unconfirmed actions to impair SARS-CoV-2 infection in humans.

Indexed as

Antiviral peptidesAquatic organismCOVID-19SARS-CoV-2Virus

Identifiers

PMID33883784
PMCPMC8049179
OpenAlexW3156184497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.