Evidence map›Paper›PMID 33883745›Full record

ArticleNature2021

Mouse prefrontal cortex represents learned rules for categorization.

Sandra Reinert, Mark Hübener, Tobias Bonhoeffer, Pieter M Goltstein

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 141 citations in OpenAlex.

  1. Population geometries in frontal cortex coordinate value-based decisions.bioRxiv : the preprint server for biology · 2026
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  5. In-depth characterization of the CaScientific reports · 2026
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  14. Meta-learning is expressed through altered prefrontal cortical dynamics.bioRxiv : the preprint server for biology · 2026
    Article
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  20. Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sandra ReinertMax Planck Institute of Neurobiology, Martinsried, Germany.
Mark HübenerMax Planck Institute of Neurobiology, Martinsried, Germany.ORCID http://orcid.org/0000-0001-8367-9132
Tobias BonhoefferMax Planck Institute of Neurobiology, Martinsried, Germany.ORCID http://orcid.org/0000-0001-7897-6634
Pieter M GoltsteinMax Planck Institute of Neurobiology, Martinsried, Germany. goltstein@neuro.mpg.de.ORCID http://orcid.org/0000-0001-8895-0841
Max Planck Institute of Neurobiology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to categorize sensory stimuli is crucial for an animal's survival in a complex environment. Memorizing categories instead of individual exemplars enables greater behavioural flexibility and is computationally advantageous. Neurons that show category selectivity have been found in several areas of the mammalian neocortex

Indexed as

Models, NeurologicalAnimalsFemaleLearningMemoryMiceMice, Inbred C57BLNeuronsPattern Recognition, VisualPhotic StimulationPrefrontal CortexTime Factors

Identifiers

PMID33883745
PMCPMC8131197
OpenAlexW3153243121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.