ArticleScientific reports2021
Effect of four different forms of high intensity training on BDNF response to Wingate and Graded Exercise Test.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Effect of Calorie Restriction and Intermittent Fasting Regimens on Brain-Derived Neurotrophic Factor Levels and Cognitive Function in Humans: A Systematic Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Exercise improves depression through positive modulation of brain-derived neurotrophic factor (BDNF). A review based on 100 manuscripts over 20 years.Frontiers in physiology · 2023Pooled it
- High-intensity interval training differentially modulates acute BDNF and cognitive responses in young adult males: a randomized crossover trial.Scientific reports · 2026Trial
- Trial
- Divergent effects of high-intensity functional training and moderate-intensity continuous training in adolescents with overweight/obesity: a randomized controlled trial on body composition, physical fitness, and psychological health.Frontiers in physiology · 2026Trial
- Acute high-intensity interval training, but not reduced-exertion high-intensity interval training increase brain-derived neurotrophic factor in a block randomized controlled trial.Scientific reports · 2025Trial
- An examination into the mental and physical effects of a saffron extract (affron®) in recreationally-active adults: A randomized, double-blind, placebo-controlled study.Journal of the International Society of Sports Nutrition · 2022Trial
- Individual response to continuous and interval training on cognitive and brain-derived neurotrophic factor in adolescents with overweight/obesity.Pediatric research · 2026Article
- Beyond cortisol: evaluating serotonin, brain-derived neurotrophic factor, and oxytocin as indicators of equine welfare across three training regimens.BMC veterinary research · 2026Article
- Risk of Rhabdomyolysis and Kidney Injury after Intensive Exercise. Potential of Novel Biomarkers of Kidney Injury: A Narrative Review.Journal of human kinetics · 2026Review
- Neurophysiological mechanisms underlying cardiovascular adaptations to exercise: A narrative review.Physiological reports · 2025Review
- The Impact of Modified Tabata Training on Segmental Fat Accumulation, Muscle Mass, Muscle Thickness, and Physical and Cardiorespiratory Fitness in Overweight and Obese Participants: A Randomized Control Trial.Sports (Basel, Switzerland) · 2025Article
- Cognitive rehabilitation among long COVID patients using vibratory and auditory treatment (VAT) is linked to BDNF.Frontiers in cognition · 2025Article
- Effects of two forms of school-based high-intensity interval training on body fat, blood pressure, and cardiorespiratory fitness in adolescents: randomized control trial with eight-week follow-up-the PEER-HEART study.Frontiers in physiology · 2025Article
- Resisting decline: the neuroprotective role of resistance exercise in supporting cerebrovascular function and brain health in aging.Frontiers in physiology · 2025Review
- Role of Cardiorespiratory Fitness, Aerobic, Exercise and Sports Participation in Female Cognition: A Scoping Review : Sports, Fitness, and Cognition.Sports medicine - open · 2024Article
- Review
- Therapeutic Importance of Exercise in Neuroplasticity in Adults with Neurological Pathology: Systematic Review.International journal of exercise science · 2024Review
- Acute effect of moderate and high-intensity interval exercises on asprosin and BDNF levels in inactive normal weight and obese individuals.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study examined the effects of a nine-week intervention of four different high-intensity training modalities [high-intensity functional training (HIFT), high-intensity interval training (HIIT), high-intensity power training (HIPT), and high-intensity endurance training (HIET)] on the resting concentration of brain-derived neurotropic factor (BDNF). In addition, we evaluated the BDNF responses to Graded Exercise Test (GXT) and Wingate Anaerobic Test (WAnT) in men. Thirty-five healthy individuals with body mass index 25.55 ± 2.35 kg/m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.