Evidence map›Paper›PMID 33883266›Full record

ArticlemSphere2021

Ehrlichia chaffeensis TRP120 Is a Wnt Ligand Mimetic That Interacts with Wnt Receptors and Contains a Novel Repetitive Short Linear Motif That Activates Wnt Signaling.

Madison R Rogan, LaNisha L Patterson, Caitlan D Byerly, Tian Luo, Slobodan Paessler, Veljko Veljkovic, Bethany Quade, Jere W McBride

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Cell signaling inFrontiers in cellular and infection microbiology · 2025
    Review
  4. Frontiers in cell and developmental biology · 2024
    Article
  5. Infection and immunity · 2023
    Article
  6. Infection and immunity · 2023
    Article
  7. bioRxiv : the preprint server for biology · 2023
    Article
  8. Type 1 secretion system and effectors in Rickettsiales.Frontiers in cellular and infection microbiology · 2023
    Review
  9. Frontiers in cellular and infection microbiology · 2023
    Review
  10. Article
  11. Article
  12. mBio · 2022
    Article
  13. Moonlighting in Rickettsiales: Expanding Virulence Landscape.Tropical medicine and infectious disease · 2022
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Madison R RoganDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
LaNisha L PattersonDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Caitlan D ByerlyDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Tian LuoDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0003-4360-3429
Slobodan PaesslerDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0002-2213-9551
Veljko VeljkovicBiomedProtection, LLC, Galveston, Texas, USA.
Bethany QuadeDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Jere W McBrideDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA jemcbrid@utmb.edu.ORCID 0000-0003-3335-1539
The University of Texas Medical Branch at Galveston · USBiomed Protection (United States) · US

Funding

EMERGING AND TROPICAL INFECTIOUS DISEASEST32AI007526 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI SOONG, LYNN · 1997 to 2025
$3.1M
Molecular basis of Wnt activation by Ehrlichia Wnt ligand mimicsR21AI149136 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MCBRIDE, JERE W · 2020 to 2021
$426k
Wnt signaling during Ehrlichia infectionR21AI126144 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MCBRIDE, JERE W · 2016 to 2017
$420k
Characterizing Notch Ligand Mimic Function of the Ehrlichia TRP120 Effector in Suppression of Host Cell ApoptosisF31AI152424 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PATTERSON, LANISHA · 2020 to 2021
$69k
NIAID NIH HHS F31 AI152424NIAID NIH HHS R21 AI126144NIAID NIH HHS R21 AI149136NIAID NIH HHS T32 AI007526
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ProteinsEhrlichia chaffeensisHost-Pathogen InteractionsHumansLigandsMonocytesReceptors, WntTHP-1 CellsWnt Signaling PathwayBacterial ProteinsLigandsReceptors, WntEhrlichia chaffeensisSLiMtandem repeatTRP120Wnt ligand

Identifiers

PMID33883266
PMCPMC8546699
OpenAlexW3153109764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.