ArticleScience advances2021
Glucocorticoid exposure predicts survival in female baboons.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 59 citations in OpenAlex.
- Article
- Using insertable cardiac monitors to test determinants of heart rate and activity in captive baboons.Animal biotelemetry · 2026Article
- Group traits moderate the relationship between individual social traits and fitness in gorillas.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Is Early Life Adversity Associated With Adult Stress in a Wild Rodent?Ecology and evolution · 2025Article
- Stress responsiveness in a wild primate predicts survival across an extreme El Niño drought.Science advances · 2025Article
- A female-biased gene expression signature of dominance in cooperatively breeding meerkats.Molecular ecology · 2024Article
- Using non-invasive behavioral and physiological data to measure biological age in wild baboons.GeroScience · 2024Article
- More allogrooming is followed by higher physiological stress in wild female baboons.Biology letters · 2024Article
- Review
- Social network shrinking is explained by active and passive effects but not increasing selectivity with age in wild macaques.Proceedings. Biological sciences · 2024Article
- A positive effect of cumulative intergroup threat on reproductive success.Proceedings. Biological sciences · 2023Article
- Natural Animal Populations as Model Systems for Understanding Early Life Adversity Effects on Aging.Integrative and comparative biology · 2023Article
- Social and early life determinants of survival from cradle to grave: A case study in wild baboons.Neuroscience and biobehavioral reviews · 2023Review
- Re-wilding model organisms: Opportunities to test causal mechanisms in social determinants of health and aging.Neuroscience and biobehavioral reviews · 2023Review
- Sex bias in mortality risk changes over the lifespan of bottlenose dolphins.Proceedings. Biological sciences · 2023Article
- Genetic variance and indirect genetic effects for affiliative social behavior in a wild primate.Evolution; international journal of organic evolution · 2023Article
- A Causal Mediation Model for Longitudinal Mediators and Survival Outcomes with an Application to Animal Behavior.Journal of agricultural, biological, and environmental statistics · 2023Article
- Shared community effects and the non-genetic maternal environment shape cortisol levels in wild chimpanzees.Communications biology · 2023Article
- Early life adversity and adult social relationships have independent effects on survival in a wild primate.Science advances · 2023Article
- Quantifying allo-grooming in wild chacma baboons (Royal Society open science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
Are differences in hypothalamic-pituitary-adrenal (HPA) axis activation across the adult life span linked to differences in survival? This question has been the subject of considerable debate. We analyze the link between survival and fecal glucocorticoid (GC) measures in a wild primate population, leveraging an unusually extensive longitudinal dataset of 14,173 GC measurements from 242 adult female baboons over 1634 female years. We document a powerful link between GCs and survival: Females with relatively high current GCs or high lifelong cumulative GCs face an elevated risk of death. A hypothetical female who maintained GCs in the top 90% for her age across adulthood would be expected to lose 5.4 years of life relative to a female who maintained GCs in the bottom 10% for her age. Hence, differences among individuals in HPA axis activity provide valuable prognostic information about disparities in life span.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.