ArticleScience advances2021
Mechanisms of neuro-robotic prosthesis operation in leg amputees.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 82 citations in OpenAlex.
- Embroidered textile sensors for real-time multiaxial force mapping in prosthetics.Science advances · 2026Article
- Decoding phantom limb movements from intraneural recordings.Nature communications · 2026Article
- The SoftFoot Pro: an anthropomorphic and adaptive soft articulated prosthetic foot.Nature communications · 2026Article
- Artificial-Intelligence-Driven Electromyography Adaptation for Elderly Assistance at Physiological, Functional, and Behavioral Levels.Cyborg and bionic systems (Washington, D.C.) · 2026Article
- Development and assessment of vibrotactile feedback from the embedded sensors of a microprocessor-controlled knee prosthesis.Journal of neuroengineering and rehabilitation · 2025Article
- A worldwide research overview of Artificial Proprioception in prosthetics.PLOS digital health · 2025Review
- The Next Frontier in Neuroprosthetics: Integration of Biomimetic Somatosensory Feedback.Biomimetics (Basel, Switzerland) · 2025Review
- Modulating synaptic plasticity with metal-organic framework for information-filterable artificial retina.Nature communications · 2025Article
- Intelligent prosthetic hips and knees: from actuation to perception and control.Frontiers in neuroscience · 2025Review
- Somatosensory restoration and neural control strategies in lower-limb prostheses.npj biomedical innovations · 2025Review
- Restoring Somatotopic Sensory Feedback in Lower Limb Amputees through Noninvasive Nerve Stimulation.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- Wearable non-invasive neuroprosthesis for targeted sensory restoration in neuropathy.Nature communications · 2024Article
- Clinical Applications and Future Translation of Somatosensory Neuroprostheses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Sensory integration for neuroprostheses: from functional benefits to neural correlates.Medical & biological engineering & computing · 2024Review
- Restoration of sensory feedback from the foot and reduction of phantom limb pain via closed-loop spinal cord stimulation.Nature biomedical engineering · 2024Article
- Continuous neural control of a bionic limb restores biomimetic gait after amputation.Nature medicine · 2024Article
- Neural population dynamics reveals disruption of spinal circuits' responses to proprioceptive input during electrical stimulation of sensory afferents.Cell reports · 2024Article
- Biomimetic computer-to-brain communication enhancing naturalistic touch sensations via peripheral nerve stimulation.Nature communications · 2024Article
- Automated calibration of somatosensory stimulation using reinforcement learning.Journal of neuroengineering and rehabilitation · 2023Article
- The impact of walking on the perception of multichannel electrotactile stimulation in individuals with lower-limb amputation and able-bodied participants.Journal of neuroengineering and rehabilitation · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Above-knee amputees suffer the lack of sensory information, even while using most advanced prostheses. Restoring intraneural sensory feedback results in functional and cognitive benefits. It is unknown how this artificial feedback, restored through a neuro-robotic leg, influences users' sensorimotor strategies and its implications for future wearable robotics. To unveil these mechanisms, we measured gait markers of a sensorized neuroprosthesis in two leg amputees during motor tasks of different difficulty. Novel sensorimotor strategies were intuitively promoted, allowing for a higher walking speed in both tasks. We objectively quantified the augmented prosthesis' confidence and observed the reshaping of the legs' kinematics toward a more physiological gait. In a possible scenario of a leg amputee driving a conventional car, we showed a finer pressure estimation from the prosthesis. Users exploited different features of the neural stimulation during tasks, suggesting that a simple prosthesis sensorization could be effective for future neuro-robotic prostheses.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.