Evidence map›Paper›PMID 33882970›Full record

Trial reportJournal of cardiothoracic surgery2021

Dexmedetomidine combined with sufentanil and dezocine-based patient-controlled intravenous analgesia increases female patients' global satisfaction degree after thoracoscopic surgery.

Qiongzhen Li, Haixia Yao, Meiying Xu, Jingxiang Wu

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cardiothoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effect of Dexmedetomidine on the EDDrug design, development and therapy · 2025
    Trial
  4. Trial
  5. Article
  6. Mechanism, Dose, and Administration of Dexmedetomidine in Managing Visceral Pain Associated With Surgery: A Narrative Review.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Qiongzhen Li *Department of Anesthesiology of Shanghai Chest Hospital, Shanghai Jiaotong University, No. 241 Huaihai Rd. West, Shanghai, 200025, China.
Haixia Yao *Department of Anesthesiology of Shanghai Chest Hospital, Shanghai Jiaotong University, No. 241 Huaihai Rd. West, Shanghai, 200025, China.
Meiying XuDepartment of Anesthesiology of Shanghai Chest Hospital, Shanghai Jiaotong University, No. 241 Huaihai Rd. West, Shanghai, 200025, China.
Jingxiang WuDepartment of Anesthesiology of Shanghai Chest Hospital, Shanghai Jiaotong University, No. 241 Huaihai Rd. West, Shanghai, 200025, China. Wu_jingxiang@shchest.org.ORCID http://orcid.org/0000-0003-1471-5640
Shanghai Chest Hospital · CN

Funding

National Natural Science Foundation of China 81671078
6 · The paper itself

Abstract

backgroundThere are no studies on the use of dexmedetomidine combined with sufentanil and dezocine-based patient-controlled intravenous analgesia (PCIA) in females undergoing thoracic surgery. We postulate that introducing dexmedetomidine to a combination of dezocine-based PCA drugs and sufentanil will increase female patients' global satisfaction degree.

methodsOne hundred fifty-two female patients with physical classification type I or II according to the American Society of Anesthesiologists undergoing thoracoscopic surgery were arbitrarily classified into two categories, either receiving sufentanil and dezocine-based PCIA (group C) or incorporating dexmedetomidine with sufentanil and dezocine-based PCIA (group D). The patients' global satisfaction degree, postoperative nausea and vomiting (PONV), PCA bolus, rescue analgesia requirements, drug-related adverse effects, rest and coughing visual analogue scale (VAS) ratings, and Ramsay sedation scores (RSS) were measured at 6, 12, 24, 36 and 48 h after surgery.

resultsCompared with the C group, the patient satisfaction degree was significantly higher; pain scores at rest and coughing were significantly different at 6, 12, 24, 36 and 48 h postoperatively; less rescue analgesia and PCA bolus were required; and a lower incidence of PONV was found in the D group. There were non-significant trends for the sedation scores and drug-related adverse effects in both groups.

conclusionsDexmedetomidine combined with sufentanil and dezocine increased female patients' global satisfaction degree after thoracoscopic surgery. This effect could be linked to the improvement in postoperative analgesia and reduction in postoperative nausea and vomiting; the combined treatment did not increase drug-related adverse effects in female patients.

trial registrationChinese Clinical Trial Registry number, ChiCTR2000030429 . Registered on March 1, 2020.

Indexed as

Patient SatisfactionAdultAnalgesiaAnalgesia, Patient-ControlledAnalgesics, Non-NarcoticAnalgesics, OpioidBridged Bicyclo Compounds, HeterocyclicDexmedetomidineFemaleHumansMiddle AgedPain ManagementPain MeasurementPostoperative PainPostoperative PeriodSufentanilAnalgesics, Non-NarcoticAnalgesics, OpioidBridged Bicyclo Compounds, HeterocyclicDexmedetomidinedezocineSufentanilTetrahydronaphthalenesCombination, Thoracoscopic, Patient-Controlled Intravenous Analgesia.DexmedetomidineDezocineSatisfaction degreeSufentanil

Identifiers

PMID33882970
PMCPMC8059176
OpenAlexW3154683464

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.