Evidence map›Paper›PMID 33882898›Full record

ArticleBMC pediatrics2021

Preconceptional and prenatal exposure to diurnal temperature variation increases the risk of childhood pneumonia.

Xiangrong Zheng, Jian Kuang, Chan Lu, Qihong Deng, Haiyu Wu, Rachael Gakii Murithi, McSherry Brownel Johnson, Wang Peng, Maolan Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiangrong ZhengDepartment of Pediatrics, XiangYa Hospital, Central South University, Changsha, Hunan, China.
Jian KuangDepartment of Pediatrics, XiangYa Hospital, Central South University, Changsha, Hunan, China.
Chan LuXiangYa School of Public Health, Central South University, 410078, Changsha, Hunan, China. chanlu@csu.edu.cn.
Qihong DengXiangYa School of Public Health, Central South University, 410078, Changsha, Hunan, China.
Haiyu WuXiangYa School of Medicine, Central South University, Changsha, Hunan, China.
Rachael Gakii MurithiXiangYa School of Public Health, Central South University, 410078, Changsha, Hunan, China.
McSherry Brownel JohnsonXiangYa School of Public Health, Central South University, 410078, Changsha, Hunan, China.
Wang PengDepartment of Pediatrics, XiangYa Hospital, Central South University, Changsha, Hunan, China.
Maolan WuDepartment of Pediatrics, XiangYa Hospital, Central South University, Changsha, Hunan, China.
Central South University · CNXiangya Hospital Central South University · CN

Funding

Health and Family Planning Commission of Hunan Province B20180881Hunan Provincial Science and Technology Department 2020SK3045National Natural Science Foundation of China 42007391National Natural Science Foundation of China 81861138005National Natural Science Foundation of China (CN) 81873851Natural Science Foundation of Hunan Province 2018JJ6141the key special focus project of China Hunan Provincial Science and Technology Department 2020SK3025
6 · The paper itself

Abstract

backgroundPneumonia is the leading cause of death and hospitalization among young children worldwide, but its risk factors remain unclear.

objectiveTo evaluate the effect of maternal exposure to diurnal temperature variation (DTV) during preconceptional and prenatal periods on childhood pneumonia.

methodsA retrospective cohort study by case-control design was conducted for pneumonia (N = 699) and normal (N = 811) children under age of 14 who were enrolled in XiangYa Hospital, Changsha, China from May 2017 to April 2019. Demographic data including gender, age, birth season, gestational age, parity, mode of delivery, and parental atopy were collected from the electronic medical records in the hospital system. We obtained the data of daily DTV in Changsha during 2003-2019 from China Meteorological Administration. Maternal exposure to DTV during preconceptional and prenatal periods was respectively calculated by the average of daily DTV during one year and three months before conception and entire pregnancy as well as the three trimesters. The association between maternal exposure to outdoor DTV and childhood pneumonia was analyzed by multiple logic regression model.

resultsWe found that childhood pneumonia was significantly associated with exposure to an increase in DTV during one year before conception and entire pregnancy, with ORs (95 % CI) = 2.53 (1.56-4.10) and 1.85 (1.24-2.76). We further identified a significant risk of pneumonia of DTV exposure during the first and second trimester of pregnancy. Sensitivity analysis showed that boys were more susceptible to the effect of prenatal exposure to outdoor DTV during pregnancy particularly in the first two trimesters compared to girls.

conclusionsPreconceptional and prenatal exposure to DTV plays an important role in development of childhood pneumonia, especially during the first and second trimesters of pregnancy.

Indexed as

PneumoniaPrenatal Exposure Delayed EffectsChildChild, PreschoolChinaFemaleHumansMaleMaternal ExposurePregnancyRetrospective StudiesTemperatureChildhood pneumoniaDiurnal temperature variationPreconceptionalPregnancyTrimester

Identifiers

PMID33882898
PMCPMC8061002
OpenAlexW3125280945

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.