Evidence map›Paper›PMID 33882850›Full record

ArticleBMC infectious diseases2021

Gastrointestinal manifestations of Talaromyces marneffei infection in an HIV-infected patient rapidly verified by metagenomic next-generation sequencing: a case report.

Ying Zhou, Yongfeng Liu, Ying Wen

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. GastrointestinalFrontiers in immunology · 2022
    Pooled it
  2. Rapid diagnosis ofFrontiers in cellular and infection microbiology · 2022
    Pooled it
  3. Review
  4. Article
  5. Clinical Features and Diagnostic Challenges ofInfection and drug resistance · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. DisseminatedOpen forum infectious diseases · 2023
    Article
  15. DisseminatedFrontiers in cellular and infection microbiology · 2023
    Review
  16. Molecular Diagnosis of Endemic Mycoses.Journal of fungi (Basel, Switzerland) · 2022
    Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ying ZhouDepartment of Infectious Diseases, The First Affiliated Hospital of China Medical University, No. 155, Nanjing North Street, Heping District, Shenyang, 110001, Liaoning Province, China.
Yongfeng LiuBGI PathoGenesis Pharmaceutical Technology, BGI-Shenzhen, Shenzhen, Guangdong Province, China.
Ying WenDepartment of Infectious Diseases, The First Affiliated Hospital of China Medical University, No. 155, Nanjing North Street, Heping District, Shenyang, 110001, Liaoning Province, China. wenying666466@163.com.ORCID http://orcid.org/0000-0002-9775-6351
First Hospital of China Medical University · CNBGI Group (China) · CN

Funding

Shenyang Science and Technology Bureau 18-014-4-30
6 · The paper itself

Abstract

backgroundThe manifestation of Talaromyces marneffei infection in some HIV-infected patients may be atypical. Cases with gastrointestinal involvement have rarely been reported. It is hard to make a diagnosis when patients are lacking the characteristic rash and positive blood culture. CASE PRESENTATION: Here, we described a patient living with HIV who complained of fever and abdominal pain, and was rapidly diagnosed with Talaromyces marneffei infection by metagenomic next-generation sequencing (mNGS) using formalin-fixation and paraffin-embedded (FFPE) samples of omentum majus tissue. We also reviewed reported related cases.

conclusionsTalaromyces marneffei is an unusual cause of clinical presentations involving obvious abdominal pain and lower gastrointestinal bleeding, but can be included in the differential diagnosis. As an important diagnostic tool, the significance of mNGS using FFPE samples of lesions provides a more targeted diagnosis.

Indexed as

AdultAIDS-Related Opportunistic InfectionsAntifungal AgentsAnti-HIV AgentsChinaDiagnosis, DifferentialFollow-Up StudiesGastrointestinal HemorrhageHigh-Throughput Nucleotide SequencingHIVHumansMaleMetagenomicsMycosesRNA, ViralTalaromycesAntifungal AgentsAnti-HIV AgentsRNA, ViralGastrointestinal involvementHuman immunodeficiency virusMetagenomic next-generation sequencingTalaromyces marneffei

Identifiers

PMID33882850
PMCPMC8059157
OpenAlexW3154203155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.