Evidence map›Paper›PMID 33882797›Full record

ArticleRedox report : communications in free radical research2021

Redox imbalance in Crohn's disease patients is modulated by Azathioprine.

Mohammad Javad Tavassolifar, Mostafa Changaei, Zahra Salehi, Fatemeh Ghasemi, Moslem Javidan, Mohammad Hossein Nicknam, Mohammad Reza Pourmand

Open access · goldAbstract read
In one paragraph

Article in Redox report : communications in free radical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Assessment of Serum Dynamic Thiol/Disulfide Homeostasis and Oxidative/Nitrosative Stress in Patients with Crohn's Disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mohammad Javad TavassolifarImmunology Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mostafa ChangaeiImmunology Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Zahra SalehiImmunology Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Fatemeh GhasemiDepartment of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Moslem JavidanImmunology Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Hossein NicknamImmunology Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Reza PourmandDepartment of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCrohn's disease (CD) is a chronic inflammatory disease without a specific cause. Inflammation in these patients can disturb the oxidants/antioxidants balance and results in oxidative stress that plays a destructive role. This study aimed to evaluate the gene expression of

methodPeripheral bloodmononuclear cells (PBMCs) were separated from CD patients (

resultThe expression levels of

conclusionOverall, our results showed that prescription of Azathioprine can lead to the altered expression of redox system-related genes in patients with CD.

Indexed as

AzathioprineCrohn DiseaseAntioxidantsHumansOxidation-ReductionOxidative StressAntioxidantsAzathioprineCrohn's diseaseinflammatory bowel diseaseperipheral blood mononuclear cellreactive oxygen speciesRedox

Identifiers

PMID33882797
PMCPMC8079067
OpenAlexW3153804665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.