Evidence map›Paper›PMID 33882700›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2021

Irisin induces white adipose tissue browning in mice as assessed by magnetic resonance imaging.

Yue Chen, Jie Ding, Yufei Zhao, Shenghong Ju, Hui Mao, Xin-Gui Peng

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Therapeutic Potential of Irisin in Neurodegenerative Diseases.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Bone-muscle crosstalk under physiological and pathological conditions.Cellular and molecular life sciences : CMLS · 2024
    Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yue ChenJiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, P. R. China.
Jie DingJiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, P. R. China.
Yufei ZhaoJiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, P. R. China.
Shenghong JuJiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, P. R. China.
Hui MaoDepartment of Radiology and Imaging Sciences, Emory University, Atlanta, GA 30322-1007, USA.
Xin-Gui PengJiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, P. R. China.ORCID 0000-0003-2988-5984
Zhongda Hospital Southeast University · CNEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to track and evaluate the effect of low-dose irisin on the browning of white adipose tissue (WAT) in mice using magnetic resonance imaging (MRI) noninvasively

Indexed as

AdipocytesAdipose Tissue, BrownAdipose Tissue, WhiteAnimalsDiet, High-FatFibronectinsIodide PeroxidaseIodothyronine Deiodinase Type IIMagnetic Resonance ImagingMaleMiceMice, Inbred C57BLUncoupling Protein 1FibronectinsFNDC5 protein, mouseIodide PeroxidaseIodothyronine Deiodinase Type IIUcp1 protein, mouseUncoupling Protein 1adipocytesmetabolic diseasesObesityuncoupling protein 1white

Identifiers

PMID33882700
PMCPMC8326442
OpenAlexW3152911426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.