Evidence map›Paper›PMID 33882686›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2021

A Hydrogel Strategy to Augment Tissue Adenosine to Improve Hindlimb Perfusion.

Michael N Sayegh, Kimberly A Cooney, Woojin M Han, Lanfang Wang, Frederick Strobel, Laura M Hansen, Andrés J García, Rebecca D Levit

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Michael N SayeghDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA (M.N.S., K.A.C., L.W., L.M.H., R.D.L.).
Kimberly A CooneyDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA (M.N.S., K.A.C., L.W., L.M.H., R.D.L.).
Woojin M HanGeorge W. Woodruff School of Mechanical Engineering (W.M.H., A.J.G.), Georgia Institute of Technology, Atlanta.
Lanfang WangDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA (M.N.S., K.A.C., L.W., L.M.H., R.D.L.).
Frederick StrobelDepartment of Chemistry, Emory University, Atlanta, GA (F.S.).
Laura M HansenDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA (M.N.S., K.A.C., L.W., L.M.H., R.D.L.).
Andrés J GarcíaGeorge W. Woodruff School of Mechanical Engineering (W.M.H., A.J.G.), Georgia Institute of Technology, Atlanta.
Rebecca D LevitDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA (M.N.S., K.A.C., L.W., L.M.H., R.D.L.).
Emory University · USGeorgia Institute of Technology · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
Medical Scientist Training ProgramT32GM142617 · NIGMS · EMORY UNIVERSITY · PI Jason Yustein · 2022 to 2026
$7.0M
Very early drivers of neutrophilic inflammation in cardiac ischemia-reperfusionR01HL140223 · NHLBI · EMORY UNIVERSITY · PI Rebecca Diane Levit · 2018 to 2026
$4.4M
Hydrogels for hMSC delivery & engraftmentR01AR062368 · NIAMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI GARCIA, ANDRES J · 2012 to 2022
$3.5M
NHLBI NIH HHS R01 HL140223NIAMS NIH HHS R01 AR062368NIGMS NIH HHS T32 GM008169NIGMS NIH HHS T32 GM142617
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

Drug Carriers5'-NucleotidaseAdenosineAnimalsCells, CulturedDelayed-Action PreparationsDisease Models, AnimalDrug CompoundingFemaleHindlimbHumansHydrogelsIschemiaMaleMaleimidesMice5'-NucleotidaseAdenosineDelayed-Action PreparationsDrug CarriersHydrogelsMaleimidesPolyethylene Glycols5'-nucleotidaseadenosinehydrogelperfusionperipheral artery disease

Identifiers

PMID33882686
PMCPMC8159890
OpenAlexW3155825364

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.