ArticleCell reports2021
Subiculum as a generator of sharp wave-ripples in the rodent hippocampus.
Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Encoding Patterned Spatial Behavior in the Subiculum.Hippocampus · 2026Review
- Astrocyte Mitochondrial UCP4 Reprograms Neuronal Network Oscillations via GDNF-Dependent KCells · 2026Article
- Non-Canonical Subiculum Circuit Organization and Function.Hippocampus · 2026Review
- The perforant pathway and CA3-Schaffer collateral afferents coordinate to regulate spatial learning.Communications biology · 2026Article
- Hippocampome.org, a resource for subicular neuron types and beyond.bioRxiv : the preprint server for biology · 2025Article
- Spatiotemporal patterns differentiate hippocampal sharp-wave ripples from interictal epileptiform discharges in mice and humans.Nature communications · 2025Article
- Protocol for closed-loop optogenetic manipulation of cortical activity following hippocampal sharp-wave ripples in freely behaving rats.STAR protocols · 2025Article
- Cholecystokinin facilitates the formation of long-term heterosynaptic plasticity in the distal subiculum.Communications biology · 2025Article
- Cell-specific switch for epileptiform activity: critical role of interneurons in the mouse subicular network.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Article
- The two tales of hippocampal sharp-wave ripple content: The rigid and the plastic.Progress in neurobiology · 2023Review
- Advanced age has dissociable effects on hippocampal CA1 ripples and CA3 high frequency events in male rats.Neurobiology of aging · 2022Article
- Multiple-Timescale Representations of Space: Linking Memory to Navigation.Annual review of neuroscience · 2022Review
- Dual projecting cells linking thalamic and cortical communication routes between the medial prefrontal cortex and hippocampus.Neurobiology of learning and memory · 2022Article
- Rhythmic Memory Consolidation in the Hippocampus.Frontiers in neural circuits · 2022Article
- Subicular neurons represent multiple variables of a hippocampal-dependent task by using theta rhythm.PLoS biology · 2022Article
- Lateralization of CA1 assemblies in the absence of CA3 input.Nature communications · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Sharp wave-ripples (SWRs) represent synchronous discharges of hippocampal neurons and are believed to play a major role in memory consolidation. A large body of evidence suggests that SWRs are exclusively generated in the CA3-CA2 network. In contrast, here, we provide several lines of evidence showing that the subiculum can function as a secondary SWRs generator. SWRs with subicular origin propagate forward into the entorhinal cortex as well as backward into the hippocampus proper. Our findings suggest that the output structures of the hippocampus are not only passively facilitating the transfer of SWRs to the cortex, but they also can actively contribute to the genesis of SWRs. We hypothesize that SWRs with a subicular origin may be important for the consolidation of information conveyed to the hippocampus via the temporoammonic pathway.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.