Evidence map›Paper›PMID 33882254›Full record

ArticleDento maxillo facial radiology2021

18F-FDG PET-CT postoperative changes after maxillectomy: Findings and pitfalls in interpretation.

Tima Davidson, Johnatan Nissan, Maria Krichmar, Eyal Lotan, Shai Shrot, Iris Gluck, Paul Lawson, Ran Yahalom, Shay Duvdevani

Open access · bronzeAbstract read
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Article in Dento maxillo facial radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tima DavidsonDepartment of Nuclear Medicine, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Johnatan NissanSackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Maria KrichmarOral and Maxillofacial Surgery, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Eyal LotanSackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Shai ShrotSackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Iris GluckDepartment of Oncology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Paul LawsonDepartment of Diagnostic Imaging, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Ran YahalomOral and Maxillofacial Surgery, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Shay DuvdevaniSackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Sheba Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe investigated the findings and pitfalls of FDG-PET/CT scanning after maxillectomy with reconstruction/rehabilitation procedures, in patients with head and neck malignancies treated during nine years at one tertiary medical centre.

methodsFourteen patients (10 males), aged 22-84 years, underwent 17 reconstruction/rehabilitation maxillectomy surgeries and 35 PET/CT scans. Postoperative PET/CT findings were correlated with clinical and imaging follow-up.

resultsIncreased FDG uptake, mean SUVmax 2.4 ± 1.4 (range 0.3-4.3), was observed at the postoperative bed following 12 of 17 surgeries (71%; 10 obturators, two mesh reconstructions). Following the remaining 5/17 surgeries (three with a fat flap and two without any reconstructions), abnormal FDG uptake was not observed at the postoperative bed.CT features of postoperative sites included: non-homogeneous mixed iso/hyperdense structures (hollow or filled) with multiple surrounding and/or inside air bubbles ("sponge appearance") and mucosal thickening along the postoperative bed wall (in all cases with obturator implants); rich fat density material in reconstructions with a fat flap and in closures without reconstruction, and radiopaque elongated structures in mesh reconstructions.No correlation was found of the mean SUVmax in initial scans, with the time from the surgery date (10 ± 6 months; r=0.04,

conclusions: Increased FDG uptake, together with corresponding non-specific CT features, may persist for a prolonged period after surgery with obturators and mesh implantations, mimicking malignancy or infection. Awareness of variations in postoperative PET-CT appearance can help avoid false interpretations and redundant invasive procedures.

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographyHumansMalePositron-Emission TomographyRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18RadiopharmaceuticalsF18-FDG PET/CTmaxillectomypitfallspostoperative changesreconstruction/rehabilitation

Identifiers

PMID33882254
PMCPMC8474136
OpenAlexW3152960530

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.