Evidence map›Paper›PMID 33881582›Full record

ArticleEuropean journal of nutrition2021

Associations of dietary and lifestyle oxidative balance scores with mortality risk among older women: the Iowa Women's Health Study.

Ziling Mao, Anna E Prizment, DeAnn Lazovich, Roberd M Bostick

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Article in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ziling MaoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Mailstop 1518-002-3BB, 1518 Clifton Road NE, Atlanta, GA, 30322, USA.ORCID http://orcid.org/0000-0001-9601-2468
Anna E PrizmentDivision of Haematology, Oncology and Transplantation, Medical School, University of Minnesota, Minneapolis, MN, USA.
DeAnn LazovichMasonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
Roberd M BostickDepartment of Epidemiology, Rollins School of Public Health, Emory University, Mailstop 1518-002-3BB, 1518 Clifton Road NE, Atlanta, GA, 30322, USA. rmbosti@emory.edu.ORCID http://orcid.org/0000-0001-8626-4186

Funding

EPIDEMIOLOGY OF CANCER IN A COHORT OF OLDER WOMENR01CA039742 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI LAZOVICH, DEANN · 1985 to 2014
$8.0M
NCI NIH HHS R01 CA039742
6 · The paper itself

Abstract

purposeSubstantial basic science evidence suggests that oxidative stress may play a role in aging-related health outcomes, including cardiovascular diseases (CVD) and cancer, and oxidative stress markers were linked with all-cause and cause-specific mortality in epidemiologic studies. However, the associations of many individual dietary and lifestyle anti-/pro-oxidant exposures with mortality are inconsistent. Oxidative balance scores (OBS) that incorporated multiple dietary and lifestyle factors were previously developed and reported to reflect the collective oxidative effects of multiple exposures.

methodsWe investigated associations of 11-component dietary and 4-component (physical activity, adiposity, alcohol, and smoking) lifestyle OBS (higher scores were considered more anti-oxidative) with all-cause and cause-specific mortality among women 55-69 years of age at baseline in the prospective Iowa Women's Health Study (1986-2012). We assessed OBS-mortality associations using multivariable Cox proportional hazards regression.

resultsOf the 34,137 cancer-free women included in the analytic cohort, 18,058 died (4521 from cancer, and 6825 from CVD) during a mean/median 22.0/26.1 person-years of follow-up. Among participants in the highest relative to the lowest lifestyle OBS quintiles, the adjusted hazards ratios and their 95% confidence intervals for all-cause, all-cancer, and all-CVD mortality were 0.50 (0.48, 0.53), 0.47 (0.43, 0.52), and 0.54 (0.50, 0.58) (all P

conclusionOur findings, combined with results from previous studies, suggest that a predominance of antioxidant over pro-oxidant lifestyle exposures may be associated with lower all-cause, all-CVD, and all-cancer mortality risk.

Indexed as

Cardiovascular DiseasesLife StyleAgedDietFemaleHumansIowaOxidative StressProspective StudiesRisk FactorsWomen's HealthCohort studiesDietLifestyleMortalityOxidative stress

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.